Evidence map›Paper›PMID 39524986›Full record

ReviewTherapeutic advances in infectious disease

Identifying CNS infections in transplantation and immunomodulatory therapy.

Luisa F Alviz, Benjamin A Jones, Shruti P Agnihotri, Kiran T Thakur

Abstract readReview
In one paragraph

Review in Therapeutic advances in infectious disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Luisa F AlvizDepartment of Neurology, Columbia University Irving Medical Center, New York Presbyterian Hospital, New York, NY, USA.ORCID https://orcid.org/0009-0008-5476-8425
Benjamin A JonesDepartment of Neurology, University of Alabama at Birmingham, Birmingham, AL, USA.
Shruti P AgnihotriDepartment of Neurology, University of Alabama at Birmingham, Birmingham, AL, USA.
Kiran T ThakurDepartment of Neurology, Columbia University Irving Medical Center, New York Presbyterian Hospital, New York, NY, USA.ORCID https://orcid.org/0000-0003-0050-0323

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Opportunistic central nervous system (CNS) infections are a significant cause of morbidity and mortality in immunocompromized patients, including those undergoing transplantation and receiving immunomodulatory therapy. Particularly in these individuals, the clinical presentation of these infections may have atypical patterns, emphasizing the need to consider various diagnostic possibilities, including noninfectious conditions. Quick and accurate identification, along with prompt treatment, is crucial for improving patient outcomes. Therefore, understanding which pathogens are likely to cause infection based on factors such as timing post-transplantation, specific organ transplant, and the mechanism of action of immunomodulatory medications is essential. This review will provide a detailed description of the types of infections that may arise in the context of transplantation and immunomodulatory therapy.

Indexed as

CNS infectionsimmunomodulatory therapytransplantation

Identifiers

PMID39524986
PMCPMC11550508

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.