Evidence map›Paper›PMID 39524975›Full record

ArticleMolecular therapy. Methods & clinical development2024

An

Vidyullatha Vasireddy, Casey A Maguire, David W Anderson, Carrie Ng, Yi Gong, Florian Eichler, Stéphane Fourcade, Cristina Guilera, Andrea Onieva, Angela Sanchez and 10 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular therapy. Methods & clinical development, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
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  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Vidyullatha VasireddySwanBio Therapeutics, Inc., Philadelphia, PA, USA.
Casey A MaguireDepartment of Neurology, Massachusetts General Hospital, Charlestown, MA, USA.
David W AndersonSwanBio Therapeutics, Inc., Philadelphia, PA, USA.
Carrie NgDepartment of Neurology, Massachusetts General Hospital, Charlestown, MA, USA.
Yi GongDepartment of Neurology, Massachusetts General Hospital, Charlestown, MA, USA.
Florian EichlerDepartment of Neurology, Massachusetts General Hospital, Charlestown, MA, USA.
Stéphane FourcadeNeurometabolic Disease Laboratory, Instituto de Investigación Biomédica de Bellvitge (IDIBELL), Hospital Duran i Reynalds, Barcelona, Spain.
Cristina GuileraNeurometabolic Disease Laboratory, Instituto de Investigación Biomédica de Bellvitge (IDIBELL), Hospital Duran i Reynalds, Barcelona, Spain.
Andrea OnievaDepartment of Biochemistry and Molecular Biology and Institute of Neurosciences, Universitat Autònoma de Barcelona, Barcelona, Spain.
Angela SanchezDepartment of Biochemistry and Molecular Biology and Institute of Neurosciences, Universitat Autònoma de Barcelona, Barcelona, Spain.
Marc Leal-JuliàDepartment of Biochemistry and Molecular Biology and Institute of Neurosciences, Universitat Autònoma de Barcelona, Barcelona, Spain.
Sergi VerdésDepartment of Biochemistry and Molecular Biology and Institute of Neurosciences, Universitat Autònoma de Barcelona, Barcelona, Spain.
Inge M E DijkstraLaboratory Genetic Metabolic Diseases, Department of Laboratory Medicine, Amsterdam UMC location University of Amsterdam, Amsterdam Neuroscience, Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam, the Netherlands.
Stephan KempLaboratory Genetic Metabolic Diseases, Department of Laboratory Medicine, Amsterdam UMC location University of Amsterdam, Amsterdam Neuroscience, Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam, the Netherlands.
HongGeun ParkSwanBio Therapeutics, Inc., Philadelphia, PA, USA.
Tiffany LutzSwanBio Therapeutics, Inc., Philadelphia, PA, USA.
Sean W ClarkSwanBio Therapeutics, Inc., Philadelphia, PA, USA.
Assumpció BoschDepartment of Biochemistry and Molecular Biology and Institute of Neurosciences, Universitat Autònoma de Barcelona, Barcelona, Spain.
Aurora PujolNeurometabolic Disease Laboratory, Instituto de Investigación Biomédica de Bellvitge (IDIBELL), Hospital Duran i Reynalds, Barcelona, Spain.
Karen KozarskySwanBio Therapeutics, Inc., Philadelphia, PA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adrenomyeloneuropathy is a progressive neurodegenerative disease caused by pathogenic variants in the

Indexed as

adeno-associated virusadrenomyeloneuropathybiodistributiongene therapyhuman ABCD1in vivo mouse modelneurodegenerative diseasenonhuman primatesSBT101very-long-chain fatty acids

Identifiers

PMID39524975
PMCPMC11550353

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.