Evidence map›Paper›PMID 39524942›Full record

ArticleHCA healthcare journal of medicine2024

Nursing and Supply Chain as Critical Partners in Enterprise-Level Efforts to Prevent Hemodialysis Associated Central Line-Associated Blood Stream Infections: A Case Study.

Dana L Blayney, Julia Moody, James Pittman, Noah Zanville, Missy Pennington, Sarah A Fraker, E Jackie Blanchard

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In one paragraph

Article in HCA healthcare journal of medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Dana L BlayneyHCA Healthcare Clinical Services Group, Nashville, TN.
Julia MoodyHCA Healthcare Clinical Services Group, Nashville, TN.
James PittmanHCA Healthcare Clinical Services Group, Nashville, TN.
Noah ZanvilleHCA Healthcare Clinical Services Group, Nashville, TN.
Missy PenningtonHealthTrust Performance Group, Nashville, TN.
Sarah A FrakerHCA Healthcare Clinical Services Group, Nashville, TN.
E Jackie BlanchardHCA Healthcare Clinical Services Group, Nashville, TN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Preventing central line-associated bloodstream infections (CLABSIs) remains a critical national focus for health care facilities. This notion is particularly true for patients undergoing hemodialysis (HD), where the associated mortality rates for HD-CLABSI range from 12% to 25%. Studies show that the use of central venous catheter (CVC) end caps coated with antiseptic agents, such as chlorhexidine gluconate (CHG) on HD-CVCs, can reduce the incidence of CLABSIs. However, issues ranging from difficulty finding and maintaining an adequate (and fully standardized) supply of CHG-impregnated HD end caps and ensuring consistent practice by clinicians can prevent the use of this valuable tool. The purpose of this study is to discuss the implementation and lessons learned from a successful collaboration between supply chain and nursing standardization of the supply of CHG-impregnated HD-CVC end caps in more than 140 United States-based hospitals. Methods: The 3-year, enterprise-wide initiative to standardize supply and end cap practice as well as reduce HD CLABSIs involved 3 phases: (Phase I) piloting the change in 5 inpatient facilities; (Phase II) implementing and scaling the change across 140 hospitals; and (Phase III) stabilizing supply and hard-wiring practices. Results: Following the pilot, access to CHG-impregnated HD-CVC end caps increased more than 100-fold over the next 4 quarters, with more than 50 000 CHG HD-CVC end caps being available for use by the end of 2022. Throughout the process, review and real-time audit of HD-CVC end cap application and removal were used to standardize the practice. The review of CLABSI data over the course of the program showed a nearly 16% reduction in HD-CLABSI events per 1000 catheter days following standardization of HD-CVC end cap supply. Conclusion: Overall, our results suggest that standardizing the supply of HD-CVC end caps (which are a critical link in the infection prevention chain) was associated with a reduction in CLABSIs among patients undergoing HD. In addition, the close collaboration between supply chain and nursing was instrumental to the success of our endeavor and may serve as a model for other health systems wanting to pursue similar efforts.

Indexed as

bloodstream infectioncentral line-associated bloodstream infectioncentral venous catheterizationCLABSIcross infectionhemodialysishospital infectionssepsis

Identifiers

PMID39524942
PMCPMC11547290

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.