Evidence map›Paper›PMID 39524919›Full record

ReviewInternational journal of nanomedicine2024

Collagen-Based Nanoparticles as Drug Delivery System in Wound Healing Applications.

Kusnadi Kusnadi, Yedi Herdiana, Emma Rochima, Okta Nama Putra, Amirah Mohd Gazzali, Muchtaridi Muchtaridi

Abstract readReview
In one paragraph

Review in International journal of nanomedicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kusnadi KusnadiDepartment of Pharmacy Analysis and Medicinal Chemistry, Faculty of Pharmacy, Universitas Padjadjaran, Sumedang, 45363, Indonesia.
Yedi HerdianaDepartment of Pharmacy Analysis and Medicinal Chemistry, Faculty of Pharmacy, Universitas Padjadjaran, Sumedang, 45363, Indonesia.ORCID 0000-0001-5831-9389
Emma RochimaDepartment of Fishery, Faculty of Fisheries and Marine Sciences, Universitas Padjadjaran, Sumedang, West Java, 45363, Indonesia.
Okta Nama PutraDepartment of Pharmacy Analysis and Medicinal Chemistry, Faculty of Pharmacy, Universitas Padjadjaran, Sumedang, 45363, Indonesia.
Amirah Mohd GazzaliSchool of Pharmaceutical Sciences, Universiti Sains Malaysia, Gelugor, Penang, 11800, Malaysia.
Muchtaridi MuchtaridiDepartment of Pharmacy Analysis and Medicinal Chemistry, Faculty of Pharmacy, Universitas Padjadjaran, Sumedang, 45363, Indonesia.ORCID 0000-0002-6156-8025

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Conventional wound dressings often adhere to wounds and can cause secondary injury due to their lack of anti-inflammatory and antibacterial properties. In contrast, collagen-based nanoparticles (NPs) as drug delivery systems exhibit both biocompatibility and biodegradability, presenting a promising avenue for accelerating wound healing processes. Aims of Study: This review aims to provide a comprehensive overview of the mechanisms involved in wound healing, description of the attributes of ideal wound dressings, understanding of wound healing efficacy of collagen, exploring NPs-mediated drug delivery mechanisms in wound therapy, detailing the synthesis and fabrication techniques of collagen-based NPs, and delineating the applications of various collagen-based NPs infused wound dressings on wound healing. Methodology: This review synthesizes relevant literature from reputable databases such as Scopus, Science Direct, Google Scholar, and PubMed. Results: A diverse array of collagen-based NPs, including nanopolymers, metal NPs, nanoemulsions, nanoliposomes, and nanofibers, demonstrate pronounced efficacy in promoting wound closure and tissue regeneration. The incorporation of collagen-based NPs has not only become an agent for the delivery of therapeutics but also actively contributes to the wound healing cascade. Conclusion: In conclusion, In brief, the use of collagen-based NPs presents a compelling strategy for expediting wound healing processes.

Indexed as

BandagesCollagenNanoparticlesWound HealingAnimalsDrug Delivery SystemsHumansCollagenbiodegradabilitycollagenfabrication techniquesnanoparticleswound healing

Identifiers

PMID39524919
PMCPMC11550700

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.