Evidence map›Paper›PMID 39524701›Full record

ArticleHeliyon2024

Evaluation of a novel anti-oxidant Ubiquinol acetate (EnQ10) for its safety by

Mohan Cheluru Umesh, K M Geetha, Srinivas Seekallu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Heliyon, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Mohan Cheluru UmeshDepartment of Pharmacology, College of Pharmaceutical Sciences, Dayananda Sagar University, Bengaluru-560068, Karnataka, India.
K M GeethaDepartment of Pharmacology, College of Pharmaceutical Sciences, Dayananda Sagar University, Bengaluru-560068, Karnataka, India.
Srinivas SeekalluAnthem Biosciences Pvt. Ltd., Bommasandra Industrial Area, Phase 1, Bommasandra, Bengaluru-560099, Karnataka, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: As an active form of Coenzyme Q10 (CoQ10), Ubiquinol acetate (EnQ10) is a newly developed, chemically stable, and physiologically active novel antioxidant. In addition to its anti-oxidant properties, CoQ10 is a useful cosmetic agent for human skin. Purpose: This study goal was to examine the safety of EnQ10 using Methods: The study included testing for a number of toxicological endpoints, including skin irritation test (OECD TG 439), skin corrosion test (OECD TG 431), eye irritation test (OECD TG 492), phototoxicity test (OECD TG 432), and Mouse lymphoma assay for Results: In terms of cosmetic toxicity and genotoxicity, none of the tests that were run produced positive results for EnQ10. Conclusion: As an alternatives to animal model procedures, we utilized extensive, well known

Indexed as

Coenzyme Q10Mouse lymphoma assayPhototoxicityReconstructed human corneal-like epitheliumReconstructed human epidermisUbiquinol acetate

Identifiers

PMID39524701
PMCPMC11550575

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.