Evidence map›Paper›PMID 39524593›Full record

ReviewSurgical neurology international2024

Cerebellopontine angle pilocytic astrocytoma in adults: A systematic review.

Placido Bruzzaniti, Giovanni Pennisi, Pierfrancesco Lapolla, Pietro Familiari, Vincenza Maiola, Claudia Quintiliani, Pierluigi Alò, Michela Relucenti, Biagia La Pira, Giancarlo D'Andrea

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Surgical neurology international, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Placido BruzzanitiDepartment of Human Neurosciences, Division of Neurosurgery, Policlinico Umberto I University Hospital, Sapienza University of Rome, Rome, Italy.
Giovanni PennisiDepartment of Neurosurgery, Institute of Neurosurgery, Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy.
Pierfrancesco LapollaNuffield Department of Surgical Sciences, University of Oxford, Oxford, United Kingdom.
Pietro FamiliariDepartment of Human Neurosciences, Division of Neurosurgery, Policlinico Umberto I University Hospital, Sapienza University of Rome, Rome, Italy.
Vincenza MaiolaDepartment of Neurosurgery, Fabrizio Spaziani Hospital, Frosinone, Italy.
Claudia QuintilianiDepartment of DAFR, Pathological Anatomy, Fabrizio Spaziani Hospital, Frosinone, Italy.
Pierluigi AlòDepartment of DAFR, Pathological Anatomy, Fabrizio Spaziani Hospital, Frosinone, Italy.
Michela RelucentiDepartment of Anatomy, Histology, Forensic Medicine and Orthopedics, Policlinico Umberto I Sapienza University of Rome, Rome, Lazio, Italy.
Biagia La PiraDepartment of Neurosurgery, Fabrizio Spaziani Hospital, Frosinone, Italy.
Giancarlo D'AndreaDepartment of Neurosurgery, Fabrizio Spaziani Hospital, Frosinone, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: In adults, the cerebellopontine angle (CPA) pilocytic astrocytoma (PA) is very rare. This tumor has radiological features similar to those of a vestibular schwannoma in the few cases reported in the literature. Methods: In this study, we conducted a systematic review in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses protocol and scrutinized all original studies pertaining to pontocerebellar angle PA in adult patients. We conducted an analysis of the clinical, radiological, and molecular components of all eligible articles. We have also reported a case involving a 67-year-old male individual in whom the PA exhibited radiological characteristics similar to an epidermoid cyst. Results: After the screening phase, we found four cases of PA of the pontocerebellar angle. Three cases were identified that resembled vestibular schwannoma; however, in our case, the tumor resembled an epidermoid cyst. These uncommon tumors exhibit distinctive histological patterns and molecular characteristics (adenosine triphosphate dependent helicase (ATP- dependent helicase)+, Isocitrate dehydrogenase 1-), rendering them a potential differential diagnosis for glioblastoma (GBM). Conclusion: The CPA PA has rarely been found in adult patients and should be considered in the differential diagnosis of vestibular schwannoma and epidermoid cysts. In these rare cases, the histological characteristics of PA are significant for the differential diagnosis of GBM.

Indexed as

Cerebellopontine angleEpidermoid cystMolecular markersPilocytic astrocytomaTumor

Identifiers

PMID39524593
PMCPMC11544465

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