Evidence map›Paper›PMID 39524402›Full record

ReviewComprehensive psychoneuroendocrinology2024

Oxytocin and our place in the universe.

Julie R Korenberg

Abstract readReview
In one paragraph

Review in Comprehensive psychoneuroendocrinology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Julie R KorenbergPediatrics and Neurology, University of Utah, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Is the oxytocin-vasopressin (OT-AVP) system a part of the unseen force that subtly (in a clever and indirect way) directs our human fascination to ourselves? And is it possible that this fundamental drive is the inevitable handmaiden of the genetic selection for survival and reproduction that is played out at the level of the individual, the family and the society? Perhaps. But an equally intense biological drive to experience the unknown is intertwined and exists in the individual as "curiosity". Both are essential for survival and success of the species. Curiously, the path to understanding ourselves, the joy of discovery and joining with others on this imperial journey to the OT-AVP system may itself be driven by the same system. I have been driven and inspired to understand "Us" for some unseen reason. This chapter relates how a driving curiosity and search for meaning led to the critical training and inspired mentorship essential for developing novel genetic, cellular and imaging technologies necessary for each advance toward this deeper understanding. Specifically, the chapter describes my recognition of human "Genetics" as the hub of medicine and the language of human neurobiology. We then set out the rationale for and sequential development of four technologies (dense whole genome arrays of genomic markers integrated with the recombination map; needed to genetically dissect and define the genetic contributions to the distinct features of brain and social behavior in Down syndrome and Williams syndrome. These include generation of 1) dense whole genome arrays of genomic markers integrated with the recombination and gene maps for defining rare cases of WS differing by one or more deleted genes, 2) analytic methods for parsing genetic contributions to standardized outcomes of cognitive and behavioral data, 3) technologies using multicolor and multi temporal fluorescence

Indexed as

Chromosome and genome architectureDown syndromeHuman geneticsOxytocinReligious experienceSocial behaviorTool creationVasopressinWilliams syndrome

Identifiers

PMID39524402
PMCPMC11546525

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.