Evidence map›Paper›PMID 39524321›Full record

ArticleInternational journal of drug discovery and pharmacology2023

Controlled and Targeted Drug Delivery Using Smart Nanovectors.

Abou Bakr M Salama, Yasmin Y Salem, Tamer M A Mohamed

Abstract read
In one paragraph

Article in International journal of drug discovery and pharmacology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Abou Bakr M SalamaInstitute of Molecular Cardiology, Department of Medicine, University of Louisville, KY 40208, U.S.A.
Yasmin Y SalemInstitute of Molecular Cardiology, Department of Medicine, University of Louisville, KY 40208, U.S.A.
Tamer M A MohamedInstitute of Molecular Cardiology, Department of Medicine, University of Louisville, KY 40208, U.S.A.

Funding

Induction of Cardiomyocyte Proliferation via Transient Expression of Cell Cycle Factors as a Promising Therapy for Heart FailureR01HL147921 · NHLBI · UNIVERSITY OF LOUISVILLE · PI Tamer M A Mohamed, Jonathan Satin · 2020 to 2026
$5.3M
Mechanisms of L-type Calcium Channel Regulation in Heart Health and DiseaseR01HL166280 · NHLBI · UNIVERSITY OF KENTUCKY · PI Jonathan Satin · 2023 to 2026
$2.5M
Physiologically relevant cardiac tissue culture model for drug testing and disease modelingR15HL168688 · NHLBI · UNIVERSITY OF LOUISVILLE · PI GIRIDHARAN, GURUPRASAD A · 2023 to 2023
$464k
NHLBI NIH HHS R01 HL147921NHLBI NIH HHS R01 HL166280NHLBI NIH HHS R15 HL168688
6 · The paper itself

Abstract

The conventional drug delivery systems have several limitations, such as the high frequency of administration, several off-target effects, and the need for tissue specificity. Recently, smart drug shuttles have emerged, and the nano applications provided a new opportunity for advancing the drug delivery system to become tissue targeted and decrease the frequency of administration. The recent development of nanovectors as drug carriers has gone through several steps of evolution that ended with the development of logic-embedded nanovectors. Here, we summarize the different types of nanovectors and their applications in various clinical situations, and finally, we spot the light on the future of this area of research.

Identifiers

PMID39524321
PMCPMC11545783

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.