Evidence map›Paper›PMID 39524078›Full record

ArticleDiscover social science and health2024

"I desire to have an HIV-free baby": pregnant and breastfeeding mothers' perceptions of Viral load testing and suppression in HIV care in southwestern Uganda.

Jane Kabami, Cecilia Akatukwasa, Stella Kabageni, Joanita Nangendo, Ambrose Byamukama, Fredrick Atwiine, Valence Mfitumukiza, John Bosco Tamu Munezero, Elizabeth Arinaitwe, Andrew Mutabazi and 4 more

Registry-linked trialAbstract read
In one paragraph

Article in Discover social science and health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04122144 (Enhanced Viral Load Counseling and Standardized Peer Mother Support Study), which is not on this map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04122144 naunknown statusnot on this map

Enhanced Viral Load Counseling and Standardized Peer Mother Support Study (ENHANCED-SPS)

TypeinterventionalSponsorMakerere UniversityRan2019 to 2022Enrolled980ConditionsHIVArmsENHANCED -SPS intervention
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Jane KabamiInfectious Diseases Research Collaboration, Kampala, Uganda.
Cecilia AkatukwasaInfectious Diseases Research Collaboration, Kampala, Uganda.
Stella KabageniInfectious Diseases Research Collaboration, Kampala, Uganda.
Joanita NangendoDepartment of Medicine, Makerere University College of Health Sciences, Kampala, Uganda.
Ambrose ByamukamaInfectious Diseases Research Collaboration, Kampala, Uganda.
Fredrick AtwiineInfectious Diseases Research Collaboration, Kampala, Uganda.
Valence MfitumukizaDepartment of Nursing, Kabale School of Medicine, Kabale University, Kabale, Uganda.
John Bosco Tamu MunezeroDepartment of Nursing, Kabale School of Medicine, Kabale University, Kabale, Uganda.
Elizabeth ArinaitweInfectious Diseases Research Collaboration, Kampala, Uganda.
Andrew MutabaziInfectious Diseases Research Collaboration, Kampala, Uganda.
Peter SsebutindeDepartment of Health, Mbarara District Local Government, Mbarara, Uganda.
Phillipa MusokeDepartment of Medicine, Makerere University College of Health Sciences, Kampala, Uganda.
Moses R KamyaDepartment of Medicine, Makerere University College of Health Sciences, Kampala, Uganda.
Anne R KatahoireDepartment of Medicine, Makerere University College of Health Sciences, Kampala, Uganda.

Funding

Building Implementation Science Capacity at Makerere University to Strengthen the Response to the HIV/AIDS Epidemic in UgandaD43TW010037 · FIC · MAKERERE UNIVERSITY COLLEGE OF HEALTH SCIENCES · PI KAMYA, MOSES ROBERT, SEMITALA, FRED C · 2015 to 2025
$3.3M
FIC NIH HHS D43 TW010037
6 · The paper itself

Abstract

Introduction: Viral suppression is a critical component for preventing mother-to-child transmission of HIV(MTCT). Mothers' perceptions of viral load suppression is crucial in the attainment of successful outcomes in preventing mother to child transmission of HIV. We therefore aimed to explore the experiences and perceptions of women on viral suppression. Methods: This was a qualitative sub-study embedded in a cluster-randomized trial (NCT04122144) designed to improve viral load outcomes among pregnant and breastfeeding mothers living with HIV in four level III/IV health facilities in South-western Uganda. Thirty-two in-depth interviews were conducted with pregnant and breastfeeding women with HIV from 1st March 2020 to 30th September 2020 to explore their understanding and interpretation of viral suppression. Interviews were audio-recorded, transcribed, and coded in Dedoose software for analysis. Results: A total of 32 Women living with HIV were enrolled in this qualitative study. WLHIV explained viral suppression in the context of attaining good health and having HIV-free babies. Adherence to ART was presented as a key avenue to viral suppression. The level of engagement with providers was presented as a key attribute of attaining viral suppression. The participants narrated their experiences with viral load testing within the routine services. However, they revealed experiencing some proximate barriers to suppression including anticipated stigma, challenges with non-disclosure of HIV status, pregnancy distress, and distance to the health facility. Conclusion: The understanding and interpretation of viral suppression among pregnant and breastfeeding mothers living with HIV provides a basis for adopting behaviors leading to prevention of vertical transmission of HIV. Health care workers can support women by providing clear and culturally appropriate education about viral suppression, adherence strategies and creating a supportive and non-judgmental environment.

Indexed as

PerceptionsPregnant and breastfeeding womenViral suppression

Identifiers

PMID39524078
PMCPMC11541329

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.