Evidence map›Paper›PMID 39523781›Full record

ArticleInfluenza and other respiratory viruses2024

Effectiveness of XBB.1.5 Vaccines Against Symptomatic SARS-CoV-2 Infection in Older Adults During the JN.1 Lineage-Predominant Period, European VEBIS Primary Care Multicentre Study, 20 November 2023-1 March 2024.

Lore Merdrignac, Charlotte Laniece Delaunay, Nuno Verdasca, Lorena Vega-Piris, Joan O'Donnell, Noémie Sève, Camino Trobajo-Sanmartín, Silke Buda, Mariëtte Hooiveld, Ana Paula Rodrigues and 21 more

Abstract readMulticenter Study
In one paragraph

Article in Influenza and other respiratory viruses, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Observational
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

31 authors.

Lore MerdrignacEpidemiology Department, Epiconcept, Paris, France.
Charlotte Laniece DelaunayEpidemiology Department, Epiconcept, Paris, France.
Nuno VerdascaNational Reference Laboratory for Influenza Virus and Other Respiratory Viruses, Infectious Disease Department, National Institute of Health Doutor Ricardo Jorge, Lisbon, Portugal.
Lorena Vega-PirisNational Centre of Epidemiology, CIBERESP, Carlos III Health Institute, Madrid, Spain.
Joan O'DonnellHealth Service Executive-Health Protection Surveillance Centre, Dublin, Ireland.
Noémie SèveSorbonne Université, INSERM, Institut Pierre Louis d'Epidémiologie et de Santé Publique, IPLESP, Paris, France.
Camino Trobajo-SanmartínInstituto de Salud Pública de Navarra - IdiSNA - CIBERESP, Pamplona, Spain.
Silke BudaDepartment of Infectious Disease Epidemiology, Robert Koch Institute, Berlin, Germany.
Mariëtte HooiveldNivel, Utrecht, the Netherlands.
Ana Paula RodriguesEpidemiology Department, National Institute of Health Doutor Ricardo Jorge, Lisbon, Portugal.
Gergő TúriNational Laboratory for Health Security, Epidemiology and Surveillance Centre, Semmelweis University, Budapest, Hungary.
Neus Latorre-MargalefDepartment of microbiology, Public Health Agency of Sweden, Stockholm, Sweden.
Ivan MlinarićDivision for Epidemiology of Communicable Diseases, Croatian Institute of Public Health, Zagreb, Croatia.
Mihaela LazarNational Influenza Centre, Cantacuzino National Military Medical Institute for Research and Development, Bucharest, Romania.
Marine MaurelEpidemiology Department, Epiconcept, Paris, France.
Daniel CastrillejoServicio de Vigilancia Epidemiológica, Dirección General de Salud Pública, Consejería de Políticas Sociales y Salud Pública, Melilla, Spain.
Charlene BennettNational Virus Reference Laboratory, University College Dublin, Dublin, Ireland.
Marie-Anne Rameix-WeltiCentre National de Référence Virus des Infections Respiratoire (CNR VIR), Institut Pasteur Université Paris Cité, Paris, France.
Iván Martínez-BazInstituto de Salud Pública de Navarra - IdiSNA - CIBERESP, Pamplona, Spain.
Ralf DürrwaldNational Reference Centre for Influenza, Robert Koch Institute, Berlin, Germany.
Adam MeijerNational Institute for Public Health and the Environment, Centre for Infectious Diseases Control, Bilthoven, the Netherlands.
Aryse MeloNational Reference Laboratory for Influenza Virus and Other Respiratory Viruses, Infectious Disease Department, National Institute of Health Doutor Ricardo Jorge, Lisbon, Portugal.
Beatrix OrosziNational Laboratory for Health Security, Epidemiology and Surveillance Centre, Semmelweis University, Budapest, Hungary.
Tove Samuelsson HageyDepartment of microbiology, Public Health Agency of Sweden, Stockholm, Sweden.
Sanja Kurečić FilipovićDivision for Epidemiology of Communicable Diseases, Croatian Institute of Public Health, Zagreb, Croatia.
Frederika DijkstraNational Institute for Public Health and the Environment, Centre for Infectious Diseases Control, Bilthoven, the Netherlands.
Veronica GomezEpidemiology Department, National Institute of Health Doutor Ricardo Jorge, Lisbon, Portugal.
Sabrina BacciVaccine Preventable Diseases and Immunisation Section, European Centre for Disease Prevention and Control, Stockholm, Sweden.
Marlena KaczmarekVaccine Preventable Diseases and Immunisation Section, European Centre for Disease Prevention and Control, Stockholm, Sweden.
Esther KisslingEpidemiology Department, Epiconcept, Paris, France.
VEBIS Primary Care Vaccine Effectiveness Group

Funding

European Centre for Disease Prevention and Control ECDC/2021/019
6 · The paper itself

Abstract

We estimated XBB.1.5 vaccine effectiveness (VE) against symptomatic SARS-CoV-2 infection among adults aged ≥ 65 years during the 2023/2024 JN.1 lineage-predominant period in a European multi-country test-negative case-control study at primary care level. We estimated VE adjusted by study site, age, sex, chronic conditions and onset date. We included 220 cases and 1733 controls. The VE was 48% (95% CI: 12-71), 23% (95% CI: -11-48) and 5% (95% CI: -92-56) among those with symptom onset 1-5, 6-11, and ≥ 12 weeks after vaccination, respectively. XBB.1.5 vaccine provided short and moderate protection against JN.1 symptomatic infection.

Indexed as

COVID-19COVID-19 VaccinesSARS-CoV-2Vaccine EfficacyAgedAged, 80 and overCase-Control StudiesEuropeFemaleHumansMalePrimary Health CareVaccinationCOVID-19 Vaccinescase–control studyCOVID‐19multi‐country studyprimary careSARS‐CoV‐2test‐negative designvaccine effectiveness

Identifiers

PMID39523781
PMCPMC11551475

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.