Evidence map›Paper›PMID 39523733›Full record

ArticleSmall (Weinheim an der Bergstrasse, Germany)2025

Polydopamine Nanobowl-Armoured Perfluorocarbon Emulsions: Tracking Thermal- and Photothermal-Induced Phase Change through Neutron Scattering.

Mark Louis P Vidallon, Haikun Liu, Zhenzhen Lu, Shahinur Acter, Yuyang Song, Chris Baldwin, Boon Mian Teo, Alexis I Bishop, Rico F Tabor, Karlheinz Peter and 2 more

Abstract read
In one paragraph

Article in Small (Weinheim an der Bergstrasse, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Mark Louis P VidallonMolecular Imaging and Theranostics Laboratory, Baker Heart and Diabetes Institute, 75 Commercial Road, Melbourne, VIC, 3004, Australia.ORCID 0000-0002-0026-3906
Haikun LiuMolecular Imaging and Theranostics Laboratory, Baker Heart and Diabetes Institute, 75 Commercial Road, Melbourne, VIC, 3004, Australia.ORCID 0000-0001-8050-2737
Zhenzhen LuDepartment of Chemical Engineering, University of Melbourne, Parkville, 3010, Australia.
Shahinur ActerDepartment of Radiation Oncology and Molecular Sciences, The Johns Hopkins School of Medicine, Johns Hopkins University, 733 N Broadway, Baltimore, MD, 21205, USA.ORCID 0000-0001-7908-3870
Yuyang SongMolecular Imaging and Theranostics Laboratory, Baker Heart and Diabetes Institute, 75 Commercial Road, Melbourne, VIC, 3004, Australia.ORCID 0000-0002-0973-2078
Chris BaldwinAustralian Nuclear Science and Technology Organization (ANSTO), New Illawarra Rd, Lucas Heights, NSW, 2234, Australia.
Boon Mian TeoSchool of Chemistry, Monash University, Clayton, VIC, 3800, Australia.
Alexis I BishopSchool of Physics and Astronomy, Monash University, Clayton, VIC, 3800, Australia.ORCID 0000-0001-5905-6170
Rico F TaborSchool of Chemistry, Monash University, Clayton, VIC, 3800, Australia.ORCID 0000-0003-2926-0095
Karlheinz PeterBaker Department of Cardiometabolic Health, University of Melbourne, Parkville, VIC, 3010, Australia.ORCID 0000-0002-8040-2258
Liliana de CampoAustralian Nuclear Science and Technology Organization (ANSTO), New Illawarra Rd, Lucas Heights, NSW, 2234, Australia.ORCID 0000-0003-4799-2935
Xiaowei WangMolecular Imaging and Theranostics Laboratory, Baker Heart and Diabetes Institute, 75 Commercial Road, Melbourne, VIC, 3004, Australia.ORCID 0000-0001-8658-7399

Funding

PAI-1 Targeted Intrapleural Fibronolytic TherapyP50HL107186 · NHLBI · UNIVERSITY OF TEXAS HLTH CTR AT TYLER · PI IDELL, STEVEN, KOMISSAROV, ANDREY · 2011 to 2012
$868k
Australian Institute of Nuclear Science and Engineering (AINSE Ltd.) ALNSTU13343Australian Nuclear Science and Technology Organisation P15418Australian Research Council FT160100191Melbourne University ScholarshipNational Health and Medical Research Council 1174098National Heart Foundation of Australia 106761National Heart Foundation of Australia 107186The CASS Foundation 11308
6 · The paper itself

Abstract

Anisotropic polydopamine nanobowls (PDA NBs) show significant promise in biomedicine, distinguished by their unique optical properties and superior cellular uptake compared to spherical nanoparticles. This study presents a novel approach for creating multistimuli-activated PDA NB-armored emulsions, encapsulating perfluorohexane (NB-H) and perfluoropentane (NB-P) cores, with applications in controlled delivery and ultrasound imaging. Thermal and photothermal activation induced distinct responses in the emulsions, as evidenced by optical microscopy and thermogravimetric analysis. For the first time, neutron scattering techniques (SANS and USANS) under contrast matching conditions are applied to investigate these materials, revealing detailed droplet and microbubble structures and phase transition dynamics. These results show that NB-H droplets resist phase change under direct heating, whereas NB-P droplets respond more readily, exhibiting significant bubble formation. During photothermal activation with short near-infrared (NIR) exposure (15 min at 400 mW cm

Indexed as

FluorocarbonsIndolesNanoparticlesNeutron DiffractionPolymersTemperatureEmulsionsPentanesPhase TransitionEmulsionsFluorocarbonsIndolesPentanesperflexaneperfluoropentanepolydopaminePolymersnear‐infraredneutron scatteringphase‐change emulsionspickering emulsionpolydopamine nanobowls

Identifiers

PMID39523733
PMCPMC11735900

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.