Evidence map›Paper›PMID 39523606›Full record

ArticleBritish journal of haematology2025

Genetic predisposition to vaccine-induced immune thrombotic thrombocytopenia.

Donald M Arnold, Guillaume Paré, Ishac Nazy

Abstract read
In one paragraph

Article in British journal of haematology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Anti-Platelet factor 4 immunothrombosis-not just heparin and vaccine triggers.Research and practice in thrombosis and haemostasis · 2025
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Donald M ArnoldMichael G. DeGroote Centre for Transfusion Research, McMaster University, Hamilton, Ontario, Canada.ORCID https://orcid.org/0000-0003-0943-8853
Guillaume ParéDepartment of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada.
Ishac NazyMichael G. DeGroote Centre for Transfusion Research, McMaster University, Hamilton, Ontario, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vaccine-induced immune thrombotic thrombocytopenia (VITT) is a rare prothrombotic disorder with a unique clonality-restricted immunological profile. The study by Petito and Bury et al. provides insight into the role of HLA polymorphisms and an inherent predisposition to VITT. Commentary on: Petito et al. Association of human leucocyte antigen loci with vaccine-induced immune thrombotic thrombocytopenia: Potential role of the interaction between platelet factor 4-derived peptides and MHC-II. Br J Haematol 2025; 206:290-295.

Indexed as

Genetic Predisposition to DiseasePurpura, Thrombocytopenic, IdiopathicPurpura, Thrombotic ThrombocytopenicVaccinesHLA AntigensHumansHLA AntigensVaccinesclonality‐restricted immunological profileheparin‐induced thrombocytopeniaHLAPF4‐derived peptidesvaccine‐induced immune thrombotic thrombocytopenia

Identifiers

PMID39523606
PMCPMC11739747

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.