Evidence map›Paper›PMID 39523430›Full record

ArticleLight, science & applications2024

Bessel beam optical coherence microscopy enables multiscale assessment of cerebrovascular network morphology and function.

Lukas Glandorf, Bastian Wittmann, Jeanne Droux, Chaim Glück, Bruno Weber, Susanne Wegener, Mohamad El Amki, Rainer Leitgeb, Bjoern Menze, Daniel Razansky

Abstract read
In one paragraph

Article in Light, science & applications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Preclinical in-vivo cerebrovascular imaging in rodent models: Methods and applications in Alzheimer's disease.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2026
    Review
  2. Article
  3. Article
  4. The way of life: The network challenge of blood flow in the brain.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  5. Article
  6. Metalens for passive generation of a droplet Bessel beam.Microsystems & nanoengineering · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Lukas GlandorfInstitute of Pharmacology and Toxicology & Institute for Biomedical Engineering, Faculty of Medicine, University of Zurich, Zurich, Switzerland.ORCID http://orcid.org/0000-0003-4968-2906
Bastian WittmannDepartment of Quantitative Biomedicine, University of Zurich, Zurich, Switzerland.
Jeanne DrouxDepartment of Neurology, University Hospital Zurich and University of Zurich, Zurich, Switzerland.
Chaim GlückInstitute of Pharmacology and Toxicology & Institute for Biomedical Engineering, Faculty of Medicine, University of Zurich, Zurich, Switzerland.
Bruno WeberInstitute of Pharmacology and Toxicology & Institute for Biomedical Engineering, Faculty of Medicine, University of Zurich, Zurich, Switzerland.
Susanne WegenerDepartment of Neurology, University Hospital Zurich and University of Zurich, Zurich, Switzerland.ORCID http://orcid.org/0000-0003-4369-7023
Mohamad El AmkiDepartment of Neurology, University Hospital Zurich and University of Zurich, Zurich, Switzerland.ORCID http://orcid.org/0000-0003-1245-5283
Rainer LeitgebCenter for Medical Physics and Biomedical Engineering, Medical University Vienna, Vienna, Austria.ORCID http://orcid.org/0000-0002-0131-4111
Bjoern MenzeDepartment of Quantitative Biomedicine, University of Zurich, Zurich, Switzerland.
Daniel RazanskyInstitute of Pharmacology and Toxicology & Institute for Biomedical Engineering, Faculty of Medicine, University of Zurich, Zurich, Switzerland. daniel.razansky@uzh.ch.ORCID http://orcid.org/0000-0001-8676-0964

Funding

High-Resolution Bidirectional Optical-Acoustic Mesoscopic Neural Interface for Image-Guided Neuromodulation in Behaving Animals - RF1 Admin SupplementRF1NS126102 · NINDS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI CAMPBELL, ROBERT E., RAZANSKY, DANIEL · 2022 to 2024
$3.1M
Foundation for the National Institutes of Health (Foundation for the National Institutes of Health, Inc.) RF1-NS126102NINDS NIH HHS RF1 NS126102Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (Swiss National Science Foundation) 310030_192757Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (Swiss National Science Foundation) 310030_200703
6 · The paper itself

Abstract

Understanding the morphology and function of large-scale cerebrovascular networks is crucial for studying brain health and disease. However, reconciling the demands for imaging on a broad scale with the precision of high-resolution volumetric microscopy has been a persistent challenge. In this study, we introduce Bessel beam optical coherence microscopy with an extended focus to capture the full cortical vascular hierarchy in mice over 1000 × 1000 × 360 μm

Identifiers

PMID39523430
PMCPMC11551179

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.