Evidence map›Paper›PMID 39523386›Full record

ArticleScientific reports2024

A deep learning-based method for assessing tricuspid regurgitation using continuous wave Doppler spectra.

Shenghua Xie, Han Liu, Li Su, Jie Shen, Junwang Miao, Duo Huang, Mi Zhou, Huiruo Liu, Yan Li, Lixue Yin and 2 more

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Clinical Applications of Artificial Intelligence in Structural Heart Disease.Journal of the Society for Cardiovascular Angiography & Interventions · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Shenghua Xie *Ultrasound in Cardiac Electrophysiology and Biomechanics Key Laboratory of Sichuan Province, Sichuan Clinical Research Center for Cardiovascular Disease, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, 610072, China.
Han Liu *School of Computer Science and Software Engineering, Southwest Petroleum University, Chengdu, 610500, China.
Li SuDepartment of Cardiovascular Medicine, Chengdu Fifth People's Hospital (The Second Clinical Medical College, Affiliated Fifth People's Hospital of Chengdu University of Traditional Chinese Medicine), Chengdu, 611137, China.
Jie ShenDepartment of Ultrasound Medicine, People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, 530021, China.
Junwang MiaoShanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Third Hospital of Shanxi Medical University, Tongji Shanxi Hospital, Taiyuan, 030032, China.
Duo HuangAffiliated Hospital of North Sichuan Medical College, Nanchong, 637000, China.
Mi ZhouDepartment of Ultrasound in Medicine, Chengdu Wenjiang District People's Hospital, Chengdu, 611130, China.
Huiruo LiuDepartment of Ultrasound, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450000, China.
Yan LiNanchong Central Hospital (Beijing Anzhen Hospital Nanchong Hospital), the Second Clinical College of North Sichuan Medical College, Nanchong, 637003, China.
Lixue YinUltrasound in Cardiac Electrophysiology and Biomechanics Key Laboratory of Sichuan Province, Sichuan Clinical Research Center for Cardiovascular Disease, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, 610072, China. yinlixue_cardiac@163.com.
Qinglan ShuUltrasound in Cardiac Electrophysiology and Biomechanics Key Laboratory of Sichuan Province, Sichuan Clinical Research Center for Cardiovascular Disease, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, 610072, China. qinglanshu@163.com.
Yi WangUltrasound in Cardiac Electrophysiology and Biomechanics Key Laboratory of Sichuan Province, Sichuan Clinical Research Center for Cardiovascular Disease, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, 610072, China. wangyihdl@126.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transthoracic echocardiography (TTE) is widely recognized as one of the principal modalities for diagnosing tricuspid regurgitation (TR). The diagnostic procedures associated with conventional methods are intricate and labor-intensive, with human errors leading to measurement variability, with outcomes critically dependent on the operators' diagnostic expertise. In this study, we present an innovative assessment methodology for evaluating TR severity utilizing an end-to-end deep learning system. This deep learning system comprises a segmentation model of single cardiac cycle TR continuous wave (CW) Doppler spectra and a classification model of the spectra, trained on the TR CW Doppler spectra from a cohort of 11,654 patients. The efficacy of this intelligent assessment methodology was validated on 1500 internal cases and 573 external cases. The receiver operating characteristic (ROC) curves of the internal validation results indicate that the deep learning system achieved the areas under curve (AUCs) of 0.88, 0.84, and 0.89 for mild, moderate, and severe TR, respectively. The ROC curves of the external validation results demonstrate that the system attained the AUCs of 0.86, 0.79, and 0.87 for mild, moderate, and severe TR, respectively. Our study results confirm the feasibility and efficacy of this novel intelligent assessment method for TR severity.

Indexed as

Deep LearningROC CurveTricuspid Valve InsufficiencyAgedEchocardiography, DopplerFemaleHumansMaleMiddle AgedSeverity of Illness Index

Identifiers

PMID39523386
PMCPMC11551186

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.