Evidence map›Paper›PMID 39523355›Full record

ReviewJournal of medical case reports2024

Spontaneous cerebrospinal fluid rhinorrhoea: a case report and literature review.

Umashri Sundararaju, Hamrish Kumar Rajakumar, Shanmuga Ashok Siva, Aishwarya Prateep

Abstract readCase ReportsReview
In one paragraph

Review in Journal of medical case reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Retrospective study on endonasal endoscopic management of cerebrospinal fluid rhinorrhea using pedicled nasal mucosal flap.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Umashri Sundararaju *Department of Ear-Nose-Throat, Government Medical College, Omandurar, Government Estate, Chennai, 600002, Tamilnadu, India. umashriutgml@gmail.com.ORCID http://orcid.org/0009-0004-6488-4172
Hamrish Kumar Rajakumar *Department of Ear-Nose-Throat, Government Medical College, Omandurar, Government Estate, Chennai, 600002, Tamilnadu, India. hamrishkumar2003@gmail.com.ORCID http://orcid.org/0009-0008-9642-9915
Shanmuga Ashok SivaDepartment of Ear-Nose-Throat, Government Medical College, Omandurar, Government Estate, Chennai, 600002, Tamilnadu, India.
Aishwarya PrateepDepartment of Ear-Nose-Throat, Government Medical College, Omandurar, Government Estate, Chennai, 600002, Tamilnadu, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCerebrospinal fluid rhinorrhea is a rare condition characterized by the abnormal leakage of cerebrospinal fluid from the intracranial space into the sinonasal cavity. It includes various etiologies, including traumatic, iatrogenic, and spontaneous causes, each with distinct epidemiological and clinical characteristics. CASE PRESENTATION: A 40-year-old Asian female presented with a three-month history of watery discharge from her left nostril and dull headaches localized to the left side of her head. Despite the initial diagnosis of allergic rhinitis, symptoms persisted, leading to further evaluation and eventual diagnosis of cerebrospinal fluid rhinorrhea. Detailed history, physical examination, and diagnostic tests including fluid analysis and imaging confirmed the diagnosis. The patient underwent a successful surgical repair after failed conservative management, highlighting the importance of timely intervention.

conclusionCerebrospinal fluid rhinorrhea poses significant risks if left untreated, including meningitis. Prompt recognition, accurate diagnosis, and individualized treatment strategies are crucial in mitigating complications and improving patient outcomes. A multidisciplinary approach, incorporating both conservative and surgical interventions tailored to the underlying cause, is essential for the successful management of cerebrospinal fluid rhinorrhea.

Indexed as

Cerebrospinal Fluid RhinorrheaAdultFemaleHeadacheHumansMagnetic Resonance ImagingTomography, X-Ray ComputedTreatment OutcomeAllergic rhinitisCase reportCSF rhinorrheaMisdiagnosisSpontaneous

Identifiers

PMID39523355
PMCPMC11552163

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.