Evidence map›Paper›PMID 39523324›Full record

ArticleBMC cardiovascular disorders2024

Association between the weight-adjusted-waist index and Familial hypercholesterolemia: a cross-sectional study.

Xuan Lyu, Xuanxuan Ren, Weiqing Zhang, Hanqin Zhu, Yu Wang, Jiarou Qiu, Fangying Wu, Sisi Xu, Zhaokai Jin, Minchun Yang

Abstract read
In one paragraph

Article in BMC cardiovascular disorders, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Xuan LyuZhejiang Chinese Medical University, Hangzhou, Zhejiang, 310053, China.
Xuanxuan RenZhejiang Hospital, Hangzhou, Zhejiang, 310013, China.
Weiqing ZhangZhejiang Chinese Medical University, Hangzhou, Zhejiang, 310053, China.
Hanqin ZhuZhejiang Chinese Medical University, Hangzhou, Zhejiang, 310053, China.
Yu WangHangzhou City University, Hangzhou, Zhejiang, 310015, China.
Jiarou QiuZhejiang Chinese Medical University, Hangzhou, Zhejiang, 310053, China.
Fangying WuZhejiang Chinese Medical University, Hangzhou, Zhejiang, 310053, China.
Sisi XuZhejiang Chinese Medical University, Hangzhou, Zhejiang, 310053, China.
Zhaokai JinZhejiang Chinese Medical University, Hangzhou, Zhejiang, 310053, China.
Minchun YangZhejiang Hospital, Hangzhou, Zhejiang, 310013, China. zjyyymc@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe weight-adjusted-waist index (WWI) is a novel obesity measurement indicator, and this study aims to determine the relationship between WWI and Familial hypercholesterolemia (FH).

methodsUsing data from the National Health and Nutrition Examination Survey (NHANES) from 2017 to March 2020, cross-sectional data from 3698 participants were analyzed. The study examined the correlation between WWI and FH using multivariate logistic regression and smooth curve fitting, and conducted subgroup analysis and interaction tests.

resultsThe study sample consisted of 3698 subjects for whom the overall probable prevalence of FH was 5.43% and increased with WWI tertile (quantile 1: 4.00%; quantile 2: 4.94%; quantile 3: 7.34%); individuals with the highest WWI tertile were significantly more likely to have FH than those with the lowest tertile (OR = 4.60,95% CI: 2.00-10.60). Subgroup analysis and interaction tests showed significant significance between WWI and personal history of early Atherosclerotic cardiovascular disease (ASCVD), family history of early ASCVD and probable prevalence of FH (p < 0.05).

conclusionThis study demonstrates a nonlinear positive correlation between WWI and FH. This may provide new ideas for the prevention and treatment of FH in the future.

Indexed as

Hyperlipoproteinemia Type IINutrition SurveysAdultAgedCross-Sectional StudiesFemaleHumansMaleMiddle AgedObesityPrevalenceRisk AssessmentRisk FactorsUnited StatesCross-sectional studyFamilial hypercholesterolaemiaNHANESObesityWeight-adjusted-waist index

Identifiers

PMID39523324
PMCPMC11552114

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.