Evidence map›Paper›PMID 39523286›Full record

ReviewAdvances in experimental medicine and biology2024

Machine Learning in Pain Neuromodulation.

Tessa Harland, Trish Elliott, Ilknur Telkes, Julie G Pilitsis

Abstract readReview
In one paragraph

Review in Advances in experimental medicine and biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. FPGA-Enabled, Smart Implants: A Path to Personalized Healthcare.IEEE open journal of engineering in medicine and biology · 2026
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Tessa HarlandDepartment of Neurosurgery, Albany Medical College, Albany, NY, USA.
Trish ElliottDepartment of Neurosurgery, University of Arizona College of Medicine, Tucson, AZ, USA.
Ilknur TelkesDepartment of Biomedical Science, Charles E. Schmidt College of Medicine, Florida Atlantic University, Boca Raton, FL, USA.
Julie G PilitsisDepartment of Neurosurgery, University of Arizona College of Medicine, Tucson, AZ, USA. jpilitsis@arizona.edu.

Funding

High-Resolution, Spinal Cord Stimulation for Non-Opioid Treatment of Neuropathic PainU44NS115111 · NINDS · MICRO-LEADS, INC. · PI MCLAUGHLIN, BRYAN L · 2019 to 2025
$9.8M
MR-Guided Precision Conformal Ablation Therapy for Brain TumorsR01CA166379 · NCI · WORCESTER POLYTECHNIC INSTITUTE · PI FISCHER, GREGORY S, PILITSIS, JULIE GEORGIA · 2013 to 2022
$6.5M
Reconfigurable MRI technology for safe and high-resolution imaging of deep brain stimulation at 3TR01EB030324 · NIBIB · NORTHWESTERN UNIVERSITY AT CHICAGO · PI GOLESTANI RAD, LALEH · 2021 to 2024
$2.1M
Assessment of EEG Responses to Spinal Cord Stimulation Waveforms in Chronic Pain PatientsR00NS119672 · NINDS · FLORIDA ATLANTIC UNIVERSITY · PI TELKES ERGUN, ILKNUR · 2022 to 2023
$273k
NCI NIH HHS R01 CA166379NIBIB NIH HHS R01 EB030324NINDS NIH HHS R00 NS119672NINDS NIH HHS U44 NS115111
6 · The paper itself

Abstract

This chapter highlights the intersection of pain neuromodulation and machine learning (ML), exploring current limitations in pain management and how ML techniques can address these challenges. Neuromodulation technologies, such as spinal cord stimulation (SCS), have emerged as promising interventions for chronic pain, but limitations such as patient selection have resulted in high rates of failure and costly removal of these devices. ML offers a powerful approach to augment pain management outcomes by leveraging predictive modeling for enhanced patient selection, adaptive algorithms for programming optimization, and identification of objective biomarkers for improved outcome assessment. This chapter discusses various ML applications in pain neuromodulation and how we can expect it to shape the future of the field. While ML holds great promise, challenges such as algorithm transparency, data quality, and generalizability must be addressed to fully realize its potential in revolutionizing pain management.

Indexed as

Chronic PainMachine LearningPain ManagementSpinal Cord StimulationAlgorithmsHumansPatient SelectionBiomarkersCandidate selectionChronic painMachine learningPain neuromodulationProgramming optimizationSpinal cord stimulation

Identifiers

PMID39523286
PMCPMC11841932

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.