Evidence map›Paper›PMID 39523239›Full record

GuidelineTechniques in coloproctology2024

Consensus-driven protocol for transanal irrigation in patients with low anterior resection syndrome and functional constipation.

J Martellucci, E Falletto, S Ascanelli, A Bondurri, S Borin, C Bottini, E Caproli, M Carrera, G Cestaro, L Chimisso and 36 more

Erratum issuedAbstract readPractice GuidelineReview
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In one paragraph

Guideline in Techniques in coloproctology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 5 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

46 authors.

J MartellucciUnit of Emergency Surgery, Careggi University Hospital Largo Giovanni Alessandro Brambilla, 350134, Florence, Italy. jamjac64@hotmail.com.ORCID 0000-0002-7437-9098
E FallettoDepartment of Surgical Sciences, Città Della Salute e Della Scienza, University of Torino, Turin, Italy.ORCID 0000-0001-6157-5236
S AscanelliSurgical Department, University Hospital Ferrara, Ferrara, Italy.ORCID 0000-0002-1423-8576
A BondurriDepartment of General Surgery, Department of Biomedical and Clinical Sciences, "Luigi Sacco" University Hospital, Milan, Italy.ORCID 0000-0002-6521-5876
S BorinDigestive Surgery - European Institute of Oncology, IRCCS - Milan, Milan, Italy.ORCID 0000-0001-7463-723X
C BottiniGeneral Surgery Unit, Humanitas Materdomini Institute, Castellanza (VA), Italy.ORCID 0009-0003-3271-3726
E CaproliA. Murri Hospital, Fermo, Italy.
M CarreraASL TO4, Ciriè, Turin, Italy.
G CestaroGeneral Surgery Unit, Sant'Antonio Abate Hospital in Gallarate, ASST Valle Olona, Varese, Italy.ORCID 0000-0002-9091-0731
L ChimissoDepartment of Morphology, Surgery and Experimental Medicine, General Surgery Unit, University of Ferrara, Ferrara, Italy.ORCID 0000-0002-4538-578X
G ClariziaGeneral Surgery Unit, Sondrio Civil Hospital, ASST Valtellina e Alto Lario, Sondrio, Italy.ORCID 0000-0003-0592-2904
I ClementiDepartment of Surgery "Pietro Valdoni", Policlinico Umberto I "Sapienza", University of Rome, Rome, Italy.ORCID 0000-0002-2176-2085
S CornagliaGeneral Surgery Division, Koelliker Hospital, Turin, Italy.ORCID 0009-0009-2524-6385
S CostaDepartment of General and Minimally Invasive Surgery, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.ORCID 0000-0002-8253-7754
G GalloDepartment of Surgery, Sapienza University of Rome, Rome, Italy.ORCID 0000-0003-1066-4671
C GuerciLuigi Sacco University Hospital, Milan, Italy.ORCID 0000-0002-6493-1299
C LambiaseDepartment of Translational Sciences and New Technologies in Medicine and Surgery, Gastrointestinal Unit, University of Pisa, Pisa, Italy.ORCID 0000-0002-9565-5039
A LaurettaDepartment of Surgical Oncology, Centro di Riferimento Oncologico di Aviano IRCCS, Aviano, Italy.ORCID 0000-0002-1639-3908
P LuffarelliDepartment of Pelvic Floor Surgery and Proctology, Fondazione Policlinico Universitario Campus Bio-Medico, Rome, Italy.ORCID 0000-0002-2503-8123
M C NeriPio Albergo Trivulzio Institute, Milan, Italy.
D Piccolo"G. da Saliceto" Civil Hospital in Piacenza, AUSL Piacenza, Piacenza, Italy.
E RosatiGeneral and Emergency Surgery, Santa Maria della Misericordia Hospital, Perugia, Italy.ORCID 0000-0003-2768-5989
P RossittiGastroenterology and GI Endoscopy Unit, University Hospital of Udine, Udine, Italy.
A SpoliniGeneral Surgery Unit, Sondrio Civil Hospital, ASST Valtellina e Alto Lario, Sondrio, Italy.ORCID 0000-0001-8534-3528
G TorchiaGeneral Surgery Unit, Policlinico di Bari, Bari, Italy.
E VallonciniGeneral Surgery Unit, ASST Spedali Civili di Brescia, Brescia, Italy.
D ZattoniColorectal Surgery Unit, AUSL Romagna, Ospedale per gli Infermi, Faenza, Italy.ORCID 0000-0001-7796-1262
E ZucchiGastroenterology and GI Endoscopy Unit, University Hospital of Udine, Udine, Italy.ORCID 0000-0003-2545-7587
P BiottiPelvic Floor Pathology Center, Careggi University Hospital, Florence, Italy.
A CambareriDepartment of Surgical Sciences, Città Della Salute e Della Scienza, University of Torino, Turin, Italy.
G ConiglioAzienda Sanitaria Locale di Ferrara - Distretto Centro Nord, Ferrara, Italy.
A CoppolaOU General Surgery, S. Lenonardo Hospital, Castellammare di Stabia, Naples, Italy.
K Nepote FusASL TO4, Ciriè, Turin, Italy.
S GrazianiSanta Rita Clinic, Vercelli, Italy.
M GrilliA. Murri Hospital, Fermo, Italy.
A GregoGeneral Surgery Division, Koelliker Hospital, Turin, Italy.
E GuerraSpedali Civili di Brescia Hospital, Brescia, Italy.ORCID 0000-0002-3072-4873
E LivioDepartment of General and Minimally Invasive Surgery, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
L ManganiniASST Fatebenefratelli Sacco, University Hospital, Milan, Italy.
P MazzeoVilla dei Gerani Clinic, Vibo Valencia, Italy.
A MinonneSan Camillo Forlanini Hospital, Rome, Italy.
M MirafioriDepartment of Surgical Oncology, Centro di Riferimento Oncologico di Aviano IRCCS, Aviano, Italy.
G NegriGeneral Surgery Unit, Sondrio Civil Hospital, ASST Valtellina e Alto Lario, Sondrio, Italy.ORCID 0009-0009-7906-3736
V PalazzoloOspedali Riuniti Villa Sofia-Cervello Hospital, Palermo, Italy.
C Di PasqualeDigestive Surgery - European Institute of Oncology, IRCCS - Milan, Milan, Italy.ORCID 0000-0002-7283-6777
V TantoloSurgical Department, Ostomy and Pelvic Floor Rehabilitation Center, Azienda Sanitaria Universitaria Friuli Centrale, Santa Maria della Misericordia, Udine, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study aims to establish a consensus-based standard protocol for transanal irrigation (TAI) in patients with low anterior resection syndrome (LARS) and functional constipation.

methodsThe Delphi method was utilized to reach a consensus among clinicians and nurses expert in the field of colorectal surgery and gastroenterology. To address various uncertainties concerning technical aspects, difficulties, and prescription of TAI, two questionnaires were developed and analyzed in two rounds. A binary approach was employed, setting a consensus threshold of 75% agreement.

resultsIn the first round, nurses achieved consensus on all statements, while clinicians required a second round to reach consensus, particularly regarding prescription and technical aspects. Clinicians reached consensus on prescribing TAI as a second-line treatment for LARS and functional constipation, following the failure of conservative measures such as dietary and lifestyle interventions. Timing considerations for patients with LARS encompass avoiding TAI within 1 month of stoma closure and waiting a minimum of 3 months. For functional constipation, TAI is recommended for slow transit constipation, emphasizing its preference over surgical options. Consensus was also reached on the choice of catheter for patients with LARS, training requirements for patients and caregivers, preparation of the patient's intestine before TAI, and recommended irrigations.

conclusionsThis consensus study successfully developed a standardized TAI protocol for LARS and functional constipation. It provides comprehensive guidelines for prescription and technical aspects, addressing the challenges encountered by healthcare professionals. The protocol aims to enhance patient care, improve treatment outcomes, and contribute to the advancement of TAI.

Indexed as

Clinical ProtocolsConstipationTherapeutic IrrigationAnal CanalConsensusDelphi TechniqueFemaleHumansLow Anterior Resection SyndromeMalePostoperative ComplicationsSurveys and QuestionnairesSyndromeConsensus-based protocolLARSPeristeen PlusTAI

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.