Evidence map›Paper›PMID 39523001›Full record

ArticleInternal medicine (Tokyo, Japan)2025

Acute Severe Colitis after mRNA Coronavirus Disease 2019 Vaccination.

Akira Nakanishi, Sakuma Takahashi, Tomoki Inaba, Eriko Yasutomi, Hugh Shunsuke Colvin, Koichi Izumikawa, Shigenao Ishikawa, Masaki Wato, Midori Ando, Satoko Nakamura

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Akira NakanishiDepartment of Gastroenterology, Kagawa Prefectural Central Hospital, Japan.
Sakuma TakahashiDepartment of Gastroenterology, Kagawa Prefectural Central Hospital, Japan.
Tomoki InabaDepartment of Gastroenterology, Kagawa Prefectural Central Hospital, Japan.
Eriko YasutomiDepartment of Gastroenterology, Kagawa Prefectural Central Hospital, Japan.
Hugh Shunsuke ColvinDepartment of Gastroenterology, Kagawa Prefectural Central Hospital, Japan.
Koichi IzumikawaDepartment of Gastroenterology, Kagawa Prefectural Central Hospital, Japan.
Shigenao IshikawaDepartment of Gastroenterology, Kagawa Prefectural Central Hospital, Japan.
Masaki WatoDepartment of Gastroenterology, Kagawa Prefectural Central Hospital, Japan.
Midori AndoDepartment of Pathology, Kagawa Prefectural Central Hospital, Japan.
Satoko NakamuraDepartment of Pathology, Kagawa Prefectural Central Hospital, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 74-year-old woman developed acute severe colitis after receiving her sixth mRNA vaccine against coronavirus disease 2019 (COVID-19). On the day after vaccination, she experienced bloody diarrhea, abdominal pain, and high-grade fever. Laboratory tests revealed leukocytosis and increased C-reactive protein. Contrast-enhanced computed tomography revealed bowel wall thickening with a reduced contrast effect within the colon, in addition to ascites. Sigmoidoscopy revealed extensive sloughing of the mucosa. Her symptoms and laboratory findings improved immediately after the initiation of prednisolone therapy. Pre-discharge total colonoscopy revealed mucosal repair in most of the colon. Clinicians should acknowledge that severe acute colitis can occur after COVID-19 vaccination.

Indexed as

ColitisCOVID-19COVID-19 VaccinesVaccinationAcute DiseaseAgedFemaleHumansPrednisoloneSARS-CoV-2Severity of Illness IndexTomography, X-Ray ComputedCOVID-19 VaccinesPrednisoloneacute severe colitisadverse eventCOVID-19 vaccinesmRNA vaccinesprednisolone

Identifiers

PMID39523001
PMCPMC11802211

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.