Evidence map›Paper›PMID 39523000›Full record

ArticleInternal medicine (Tokyo, Japan)2025

Enlargement of Gastric Hyperplastic Polyps Arising from Helicobacter heilmannii sensu stricto-infected Mucosa after the Successful Eradication of Helicobacter pylori and the Long-Term Use of a Proton Pump Inhibitor.

Masayuki Kurimoto, Hajime Honjo, Saki Yoshida, Natsuki Okai, Yasuo Otsuka, Yasuhiro Masuta, Sho Masaki, Ken Kamata, Kosuke Minaga, Osamu Maenishi and 2 more

Abstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Masayuki KurimotoDepartment of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Japan.
Hajime HonjoDepartment of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Japan.
Saki YoshidaDepartment of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Japan.
Natsuki OkaiDepartment of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Japan.
Yasuo OtsukaDepartment of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Japan.
Yasuhiro MasutaDepartment of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Japan.
Sho MasakiDepartment of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Japan.
Ken KamataDepartment of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Japan.
Kosuke MinagaDepartment of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Japan.
Osamu MaenishiDepartment of Pathology, Kindai University Faculty of Medicine, Japan.
Masatoshi KudoDepartment of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Japan.
Tomohiro WatanabeDepartment of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Helicobacter pylori eradication is effective for the regression of gastric hyperplastic polyps (GHPs). We report a case which demonstrated an enlargement of GHPs after H. pylori eradication. The patient, who received long-term proton-pump inhibitor (PPI) therapy, lived with a dog, a natural host of Helicobacter heilmanii sensu stricto. Gastric colonization with Helicobacter heilmannii s.s. was observed after H. pylori eradication, thus suggesting the involvement of non-H. pylori Helicobacter species (NHPHs) infection for the enlargement of GHPs, in addition to the proliferative effects of PPI use on the gastric epithelium. Screening for NHPHs may be necessary in dog lovers to avoid paradoxical responses to H. pylori eradication.

Indexed as

Gastric MucosaHelicobacter heilmanniiHelicobacter InfectionsHelicobacter pyloriPolypsProton Pump InhibitorsStomach NeoplasmsAnimalsDogsHumansHyperplasiaProton Pump Inhibitorsgastric hyperplastic polypsHelicobacter heilmannii sensu strictoHelicobacter pylorinon Helicobacter pylori Helicobacter (NHPH)

Identifiers

PMID39523000
PMCPMC12222885

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.