Evidence map›Paper›PMID 39522990›Full record

ReviewInternal medicine (Tokyo, Japan)2025

Immunoglobulin G4-related Autoimmune Hepatitis Following Type 1 Autoimmune Pancreatitis: A Case Report and Literature Review.

Chiharu Toh, Shinichi Morita, Nobutaka Takeda, Fusako Yamazaki, Kunihiko Yokoyama, Masatoshi Sato, Daisuke Kumaki, Takeshi Sakai, Kazuhiro Funakoshi, Koichi Tsuneyama

Abstract readCase ReportsReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Internal medicine (Tokyo, Japan), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Chiharu TohDepartment of Gastroenterology and Hepatology, Niigata Prefectural Central Hospital, Japan.
Shinichi MoritaDepartment of Gastroenterology and Hepatology, Niigata Prefectural Central Hospital, Japan.
Nobutaka TakedaDepartment of Gastroenterology and Hepatology, Niigata Prefectural Central Hospital, Japan.
Fusako YamazakiDepartment of Gastroenterology and Hepatology, Niigata Prefectural Central Hospital, Japan.
Kunihiko YokoyamaDepartment of Gastroenterology and Hepatology, Niigata Prefectural Central Hospital, Japan.
Masatoshi SatoDepartment of Gastroenterology and Hepatology, Niigata Prefectural Central Hospital, Japan.
Daisuke KumakiDepartment of Gastroenterology and Hepatology, Niigata Prefectural Central Hospital, Japan.
Takeshi SakaiDepartment of Pathology, Niigata Prefectural Central Hospital, Japan.
Kazuhiro FunakoshiDepartment of Gastroenterology and Hepatology, Niigata Prefectural Central Hospital, Japan.
Koichi TsuneyamaDepartment of Pathology and Laboratory Medicine, Tokushima University Graduate School of Biomedical Science, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We herein report a case of IgG4-related autoimmune hepatitis (AIH) in a patient with a history of type 1 autoimmune pancreatitis. A 56-year-old man presented with fatigue and jaundice at our hospital. A blood biochemistry analysis revealed significant liver dysfunction, positive results for antinuclear antibodies, and high serum IgG4 levels. A histopathological examination revealed interface hepatitis marked by IgG4-positive plasma cell infiltration in the portal area, leading to liver cell depletion and necrosis. Based on the diagnosis of IgG4-related AIH, prednisolone treatment was initiated, which led to the rapid resolution of liver dysfunction and jaundice. An accurate diagnosis of IgG4-related AIH is crucial to prevent secondary manifestations.

Indexed as

Autoimmune PancreatitisHepatitis, AutoimmuneImmunoglobulin GImmunoglobulin G4-Related DiseaseHumansMaleMiddle AgedPrednisoloneImmunoglobulin GPrednisoloneautoimmune hepatitisautoimmune pancreatitisimmunoglobulin G4immunoglobulin G4-related autoimmune hepatitisimmunoglobulin G4-related diseasesteroid

Identifiers

PMID39522990
PMCPMC12222882

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.