ArticleOphthalmology2025
Is Patching after Age 4 Beneficial for Children Born with a Unilateral Congenital Cataract?
Article in Ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Long-term observation of myopic shift after secondary intraocular lens implantation in children with congenital cataract and its association with preoperative ocular parameters.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Article
- Update on pediatric cataract surgery.Asia-Pacific journal of ophthalmology (Philadelphia, Pa.)Review
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
purposeThe goal of these analyses is to provide evidence that can help parents and healthcare providers determine whether or not to continue occlusion therapy once a reliable measure of optotype acuity can be obtained in children who are born with a unilateral congenital cataract.
designData from the Infant Aphakia Treatment Study (IATS) are used in a cohort design.
participantsA total of 105 children who participated in the IATS and did not have a vision-threatening adverse event.
methodsWe assessed the relationship between visual acuity (VA) at age 10.5 years and average daily hours of patching reported by caregivers on quarterly 48-hour recall interviews and annual 7-day patching diaries obtained between 48 and 60 months of age.
main outcome measuresMonocular VA was assessed at the clinic visit closest to 48 months of age using the Amblyopia Treatment Study HOTV protocol. Final VA was measured at age 10.5 years using the electronic ETDRS testing protocol.
resultsVisual acuity measurements obtained at age 4 years were reliable, with a single-measure intraclass correlation coefficient of 0.83 (95% confidence interval [CI], 0.78-0.88), and predictive of those obtained at age 10.5 years (r
conclusionsThese analyses suggest that optotype acuity measures obtained early in the fifth year of life are reliable and predictive of final visual outcomes. Additionally, our results suggest that less-aggressive patching protocols, or discontinuing patching altogether, may be justified in some children, particularly those with poor vision, once optotype acuity can be measured. However, the potential impact of latent nystagmus on uniocular VA measurement and the effect of patching on the child's quality of life, family relationships, and binocular visual field need to be considered before discontinuing occlusion therapy. FINANCIAL DISCLOSURE(S): Proprietary or commercial disclosure may be found in the Footnotes and Disclosures at the end of this article.
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