Evidence map›Paper›PMID 39522018›Full record

Trial reportBMC psychology2024

Pilot evaluation on an adapted tele-behavioral activation to increase physical activity in persons with depression: a single-arm pilot study.

Chad D Rethorst, Joseph M Trombello, Patricia M Chen, Thomas J Carmody, Lynnel C Goodman, Alejandra Lazalde, Madhukar H Trivedi

Registry-linked trialAbstract readClinical Trial
In one paragraph

Trial report in BMC psychology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04990401 (Adapted Tele-Behavioral Activation Targeted to Increase Physical Activity in Depression), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04990401 nacompletednot on this map

Adapted Tele-Behavioral Activation Targeted to Increase Physical Activity in Depression

TypeinterventionalSponsorUniversity of Texas Southwestern Medical CenterRan2021 to 2025Enrolled65ConditionsDepression, Depressive Disorder, Depressive Symptoms, Depressive EpisodeArmsBehavioral Activation Teletherapy
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Chad D RethorstInstitute for Advancing Health Through Agriculture, Texas A&M University System, Dallas, TX, USA. chad.rethorst@ag.tamu.edu.
Joseph M TrombelloDepartment of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Patricia M ChenO'Donnell School of Public Health, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Thomas J CarmodyDepartment of Population and Data Sciences, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Lynnel C GoodmanDepartment of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Alejandra LazaldeEllie Mental Health, Dallas, TX, USA.
Madhukar H TrivediDepartment of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX, USA.

Funding

Adapted Tele-Behavioral Activation Targeted to Increase Physical Activity in DepressionR34MH122640 · NIMH · UT SOUTHWESTERN MEDICAL CENTER · PI RETHORST, CHAD D, TRIVEDI, MADHUKAR H. · 2021 to 2023
$738k
NIMH NIH HHS R34 MH122640NIMH NIH HHS R34MH122640
6 · The paper itself

Abstract

backgroundPhysical activity has the potential to improve physical and mental health outcomes of persons with depression. However, feasible and acceptable strategies to integrate physical activity interventions into real-world settings are needed.

objectiveTo assess the feasibility and acceptability of a manualized Behavioral Activation intervention aimed to increase physical activity in persons with depression (defined as a PHQ-9 score ≥ 10).

methodsA single-arm pilot study was conducted. The intervention consisted of 8 tele-therapy sessions delivered over a 10-week period. Measures of feasibility included screening, enrollment, intervention adherence, outcome data availability, and intervention fidelity. Acceptability was assessed with a post-intervention survey and qualitatively through focus groups and interviews. Preliminary efficacy of the intervention was assessed by evaluating pre-to-post changes in physical activity and depressive symptoms.

resultsAll feasibility metrics exceeded predetermined feasibility goal metrics with the exception of Fitbit wear and screening rate, which was due to a greater than anticipated enrollment rate. Participants (n = 15) reported perceived benefits from the intervention and convenience in attending tele-therapy sessions. Depressive symptoms, as measured by the PHQ-9 improved (16.8 at enrollment to 10.1 post intervention, Cohen's d = 1.13). Self-reported moderate-to-vigorous physical activity (MVPA) increased from 22.0 min/week at baseline to 36.67 min/week post-intervention (d = 0.58). Physical activity as measured by the Fitbit showed little change (daily step 5543.29 during Week 1 to 6177.48 during Week 10, (d = 0.14); MVPA 21.23 min/week during Week 1 to 19.22 at Week 10 (d = 0.0.06).

conclusionsResults of the pilot study suggest the intervention is feasible to deliver and acceptable to participants. Preliminary results suggest the intervention may be effective in improving depressive symptoms and increasing self-reported physical activity.

trial registrationClinicalTrials.gov NCT04990401, Registered July 21, 2021.

Indexed as

DepressionExerciseFeasibility StudiesTelemedicineAdultBehavior TherapyFemaleHumansMaleMiddle AgedPilot ProjectsBehavioral activationDepressionExercisePhysical activity

Identifiers

PMID39522018
PMCPMC11549759

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.