Evidence map›Paper›PMID 39522009›Full record

ArticleBMC research notes2024

Predictive haemostatic biomarkers and transfusion efficacy, insights from fresh frozen plasma use in surgical patients, preliminary results.

Olivier Duranteau, Justine Decamps, Anne Daper, Philippe Cauchie, Brigitte Ickx, Turgay Tuna

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC research notes, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Olivier DuranteauAnesthesiology department, CHU Charleroi, Boulevard Zoé Drion, 1, 6000, Charleroi, Belgium. olivier.duranteau@gmail.com.
Justine DecampsAnesthesiology department, CHU Charleroi, Boulevard Zoé Drion, 1, 6000, Charleroi, Belgium.
Anne DaperAnesthesiology department, CHU Charleroi, Boulevard Zoé Drion, 1, 6000, Charleroi, Belgium.
Philippe CauchieHaemostasis Laboratory, CHU Charleroi, Charleroi, Belgium.
Brigitte IckxAnesthesiology department, CUB-ULB Erasme, Brussels, Belgium.
Turgay TunaAnesthesiology department, CUB-ULB Erasme, Brussels, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of the study was to examine various haemostasis values to identify the most relevant biological indicators for detecting significant haemorrhage, to determine the effectiveness of fresh frozen plasma (FFP) transfusion. Our findings suggest that a low prothrombin time, elevated Von Willebrand Antigen, increased plasma fibrinogen, and reduced Ca2 + levels are associated with challenges in achieving proper haemostasis. However, measurements of factors II, V, VII, VIII, IX, X, XI, XIII, protein C, and protein S do not appear to be linked to difficulties in achieving adequate haemostasis. Additionally, the administration of FFP appears to impact factors V, VII, X, and II.Trial registration EudraCT number: 2019-002898-64.

Indexed as

BiomarkersHemostasisPlasmaAdultAgedBlood Coagulation FactorsBlood Component TransfusionBlood TransfusionFemaleFibrinogenHumansMaleMiddle AgedBiomarkersBlood Coagulation FactorsFibrinogenFresh frozen plasmaHaemostasisTransfusion thresholdTransfusion yield

Identifiers

PMID39522009
PMCPMC11549873

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.