Evidence map›Paper›PMID 39522005›Full record

ArticleBMC chemistry2024

Novel pyrrole based triazole moiety as therapeutic hybrid: synthesis, characterization and anti-Alzheimer potential with molecular mechanism of protein ligand profile.

Shoaib Khan, Tayyiaba Iqbal, Muhammad Bilal Khan, Rafaqat Hussain, Yousaf Khan, Hany W Darwish

Abstract read
In one paragraph

Article in BMC chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Shoaib KhanDepartment of Chemistry, Abbottabad University of Science and Technology, Abbottabad, 22500, Pakistan. shoaibkhanswati@gmail.com.
Tayyiaba IqbalDepartment of Chemistry, Abbottabad University of Science and Technology, Abbottabad, 22500, Pakistan.
Muhammad Bilal KhanDepartment of Chemistry, Abbottabad University of Science and Technology, Abbottabad, 22500, Pakistan.
Rafaqat HussainCollege of Biology, Hunan University, Changsha, Hunan, 410082, People's Republic of China.
Yousaf KhanDepartment of Chemistry, COMSATS University Islamabad, Islamabad, 45550, Pakistan.
Hany W DarwishDepartment of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, P.O. Box 2457, 11451, Riyadh, Saudi Arabia.

Funding

King Saud University (RSPD2024R812)
6 · The paper itself

Abstract

As a springboard to explore novel potent inhibitors of cholinesterase enzymes (AChE and BChE) responsible for causing Alzheimer disorder, the current study was conducted to synthesize pyrrole derived triazole based Schiff base scaffolds by facile synthetic route. These compounds were validated by

Indexed as

AChE & BChEADMETMolecular DockingPyrroleSchiff BaseTriazole

Identifiers

PMID39522005
PMCPMC11550546

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.