Evidence map›Paper›PMID 39521975›Full record

ArticleBMC nephrology2024

Gitelman syndrome patient managed with amiloride during pregnancy and lactation.

Abdelrahman Ibrahim, Aylin R Rodan, Christof Westenfelder, Laith Al-Rabadi

Abstract readCase Reports
In one paragraph

Article in BMC nephrology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Abdelrahman IbrahimNephrology Division, Department of Internal Medicine, University of Utah Health, Salt Lake City, USA.
Aylin R RodanNephrology Division, Department of Internal Medicine, University of Utah Health, Salt Lake City, USA.
Christof WestenfelderNephrology Division, Department of Internal Medicine, University of Utah Health, Salt Lake City, USA.
Laith Al-RabadiNephrology Division, Department of Internal Medicine, University of Utah Health, Salt Lake City, USA. Laith.Al-Rabadi@hsc.utah.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gitelman Syndrome (GS) is a rare autosomal-recessive tubular disorder characterized by hypokalemia, hypomagnesemia, metabolic alkalosis, hyperreninemic hyperaldosteronism, and normotension. Management of GS during pregnancy is particularly challenging due to pregnancy-associated renal physiological changes and due to controversial safety profiles regarding teratogenicity of medications commonly used for GS management in non-pregnant patients. We report a case of a 20-year-old female patient diagnosed of GS who was treated with amiloride during pregnancy and lactation due to persistent hypokalemia resistant to oral supplementation therapy. Use of amiloride facilitated control of hypokalemia and hypomagnesemia in the mother without causing any noticeable side effects in the newborn.

Indexed as

AmilorideGitelman SyndromeLactationPregnancy ComplicationsFemaleHumansHypokalemiaPregnancyYoung AdultAmilorideAmilorideGitelmanHypokalemiaHypomagnesemiaPregnancy

Identifiers

PMID39521975
PMCPMC11550528

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.