Evidence map›Paper›PMID 39521900›Full record

ArticleCommunications biology2024

Genomic diversity and transmission patterns of Yersinia pestis in Inner Mongolia Autonomous Region, China.

Xiujuan Zuo, Fang Liu, Yanhong Hu, Xuezhi Huang, Yan Guo, Mengnan Cui, Hang Fan, Xianglilan Zhang, Zhenghua Wu, Wenrui Wang and 4 more

Abstract read
In one paragraph

Article in Communications biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Xiujuan Zuo *School of Public Health, Anhui Medical University, Hefei, China.ORCID 0009-0006-2586-2610
Fang Liu *Inner Mongolia Autonomous Region Center for Disease Control and Prevention, Hohhot, China.
Yanhong Hu *Inner Mongolia Autonomous Region Center for Disease Control and Prevention, Hohhot, China.
Xuezhi HuangSchool of Public Health, Anhui Medical University, Hefei, China.
Yan GuoState Key Laboratory of Pathogen and Biosecurity, Academy of Military Medical Sciences, Beijing, China.
Mengnan CuiState Key Laboratory of Pathogen and Biosecurity, Academy of Military Medical Sciences, Beijing, China.
Hang FanState Key Laboratory of Pathogen and Biosecurity, Academy of Military Medical Sciences, Beijing, China.
Xianglilan ZhangSchool of Public Health, Anhui Medical University, Hefei, China.
Zhenghua WuInner Mongolia Autonomous Region Center for Disease Control and Prevention, Hohhot, China.
Wenrui WangInner Mongolia Autonomous Region Center for Disease Control and Prevention, Hohhot, China.
Ruifu YangState Key Laboratory of Pathogen and Biosecurity, Academy of Military Medical Sciences, Beijing, China.ORCID 0000-0003-3219-7269
Yarong WuState Key Laboratory of Pathogen and Biosecurity, Academy of Military Medical Sciences, Beijing, China. wuyarong525@126.com.ORCID 0000-0003-4900-315X
Jianyun LiInner Mongolia Autonomous Region Center for Disease Control and Prevention, Hohhot, China. hhhtlijianyun@163.com.ORCID 0000-0002-6414-2062
Yujun CuiSchool of Public Health, Anhui Medical University, Hefei, China. cuiyujun.new@gmail.com.ORCID 0000-0001-7236-2412

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

According to WHO, plague, caused by Yersinia pestis, has resurged since 2000. Inner Mongolia, harboring a quarter of China's plague foci, has accounted for 80% of national plague cases in the past five years. Despite its pivotal role in Chinese plague epidemiology, the genetic diversity and transmission dynamics of Y. pestis in this region remain under-investigated. Our analysis of 585 Y. pestis strains from Inner Mongolia (1948-2021) revealed three primary lineages, with 2.MED3 being predominant. We further delineated seven sub-phylogroups in 2.MED3, with 2.MED3.1.2 and 2.MED3.1.4 showing recent dominance. These two subgroups reveal dual transmission patterns: localized short-distance spread and long-distance dispersals over 300 km. Xilingol League is highlighted as a key source and reservoir for Y. pestis, predominantly spreading from central-eastern to southwestern Inner Mongolia, including occasional reverse transmissions. These findings enhance understanding of Y. pestis diversity and transmission in Inner Mongolia, aiding in enhanced surveillance and control measures.

Indexed as

Genetic VariationPlagueYersinia pestisChinaGenome, BacterialHumansPhylogeny

Identifiers

PMID39521900
PMCPMC11550827

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.