ArticleScientific reports2024
Genetic variations as predictors of dispositional and dyadic empathy-a couple study.
Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Predicting Empathy and Other Mental States During VR Sessions Using Sensor Data and Machine Learning.Sensors (Basel, Switzerland) · 2025Article
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Authors and funding
3 authors.
Funding
Abstract
Biological drivers of empathy have been explored in an interdisciplinary manner for decades. Research that merges the psychological and genetic perspectives of empathy has recently gained interest, and more complex designs and analyses are needed. Empathy is a multidimensional construct that might be regarded both dispositionally (as a personality trait) and contextually (experienced and/or expressed in a particular relationship/situation). This study analyzed genetic variations associated with genes encoding oxytocin, arginine vasopressin, and receptors that regulate their secretion as predictors of the empathic dimensions of emotional (empathic concern and personal distress) and cognitive (perspective taking) dyadic factors of partners in heterosexual intimate relationships. Machine learning methods to capture both linear and nonlinear relationships between SNPs, RS1 and RS2 repeat polymorphisms and dimensions of empathy in couples were employed. A total of 442 individuals (221 couples) participated in this study. Empathy was measured by the Polish version of the Interpersonal Reactivity Index and the Interpersonal Reactivity Index for Couples. The MassARRAY® 4 instrument, which combines mass spectrometry with endpoint PCR, was used for genotyping all 14 genetic variations. Microsatellite fragment analysis was performed by denaturing polyacrylamide gel electrophoresis. The results confirmed the significance of certain genetic alterations linked to oxytocin, vasopressin, serotonin and estrogen for dispositional and dyadic empathy (mainly rs1884051, rs6311, RS1, rs4686302, and rs1042778) in couples. The effects were stronger for the prediction of emotional and dyadic empathy than for perspective taking. Separate analyses for women and men indicated different predictive effects of genes for empathy (for example, effects of rs53576 were indicated only in women), which are also experienced and expressed in couples. Different dimensions of empathy should be included when the genetic predictors of empathy are examined.
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