Evidence map›Paper›PMID 39521895›Full record

ArticleNPJ digital medicine2024

Artificial intelligence assisted operative anatomy recognition in endoscopic pituitary surgery.

Danyal Z Khan, Alexandra Valetopoulou, Adrito Das, John G Hanrahan, Simon C Williams, Sophia Bano, Anouk Borg, Neil L Dorward, Santiago Barbarisi, Lucy Culshaw and 4 more

Registry-linked trialAbstract read
In one paragraph

Article in NPJ digital medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07568366 (The Application of Artificial Intelligence to Patients Undergoing Endoscopic Transsphenoidal Surgery), which is not on this map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07568366 early_phase1not yet recruitingnot on this mapstarted 2026, after this paper: background citation

The Application of Artificial Intelligence to Patients Undergoing Endoscopic Transsphenoidal Surgery: a Single-site Prospective Feasibility and Exploratory Study (IDEAL Stage 1 and 2a)

TypeinterventionalSponsorUniversity College, LondonRan2026 to 2029Enrolled30ConditionsPituitary AdenomaArmsLive intra-op AI analysis of endoscopic video feed, with output displayed on supplementary monitor
3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Colour-Guided Surgery: A Conceptual Framework for Multimodal Intraoperative Visualisation-A Narrative Review.The international journal of medical robotics + computer assisted surgery : MRCAS · 2026
    Review
  5. Artificial intelligence-based anatomical recognition improves surgeon decision-making during robotic gastrectomy.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2026
    Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Review
  18. Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Danyal Z Khan *Department of Neurosurgery, National Hospital for Neurology and Neurosurgery, London, UK. d.khan@ucl.ac.uk.
Alexandra Valetopoulou *Department of Neurosurgery, National Hospital for Neurology and Neurosurgery, London, UK.
Adrito DasHawkes Centre, Department of Computer Science, University College London, London, UK.ORCID http://orcid.org/0000-0001-5682-9545
John G HanrahanDepartment of Neurosurgery, National Hospital for Neurology and Neurosurgery, London, UK.ORCID http://orcid.org/0000-0003-4584-2298
Simon C WilliamsDepartment of Neurosurgery, National Hospital for Neurology and Neurosurgery, London, UK.
Sophia BanoHawkes Centre, Department of Computer Science, University College London, London, UK.
Anouk BorgDepartment of Neurosurgery, National Hospital for Neurology and Neurosurgery, London, UK.
Neil L DorwardDepartment of Neurosurgery, National Hospital for Neurology and Neurosurgery, London, UK.
Santiago BarbarisiDigital Surgery Ltd, Medtronic, London, UK.
Lucy CulshawDigital Surgery Ltd, Medtronic, London, UK.
Karen KerrDigital Surgery Ltd, Medtronic, London, UK.
Imanol LuengoDigital Surgery Ltd, Medtronic, London, UK.
Danail StoyanovHawkes Centre, Department of Computer Science, University College London, London, UK.
Hani J MarcusDepartment of Neurosurgery, National Hospital for Neurology and Neurosurgery, London, UK. h.marcus@ucl.ac.uk.ORCID http://orcid.org/0000-0001-8000-392X

Funding

Wellcome Trust
6 · The paper itself

Abstract

Pituitary tumours are surrounded by critical neurovascular structures and identification of these intra-operatively can be challenging. We have previously developed an AI model capable of sellar anatomy segmentation. This study aims to apply this model, and explore the impact of AI-assistance on clinician anatomy recognition. Participants were tasked with labelling the sella on six images, initially without assistance, then augmented by AI. Mean DICE scores and the proportion of annotations encompassing the centroid of the sella were calculated. Six medical students, six junior trainees, six intermediate trainees and six experts were recruited. There was an overall improvement in sella recognition from a DICE of score 70.7% without AI assistance to 77.5% with AI assistance (+6.7; p < 0.001). Medical students used and benefitted from AI assistance the most, improving from a DICE score of 66.2% to 78.9% (+12.8; p = 0.02). This technology has the potential to augment surgical education and eventually be used as an intra-operative decision support tool.

Identifiers

PMID39521895
PMCPMC11550325

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.