Evidence map›Paper›PMID 39521845›Full record

ArticleScientific reports2024

Factors associated with outcome in a national cohort of rhinovirus hospitalized patients in Brazil in 2022.

Daniele Melo Sardinha, Marcos Jessé Abrahão Silva, Karla Valéria Batista Lima, Luana Nepomuceno Gondim Costa Lima

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Daniele Melo SardinhaPrograma de Pós-Graduação em Biologia Parasitária na Amazônia, Universidade do Estado do Pará e Instituto Evandro Chagas (PPBPA/UEPA/IEC), Belém, Pará, 66087-670, Brazil. danielle-vianna20@hotmail.com.
Marcos Jessé Abrahão SilvaPrograma de Pós-Graduação em Biologia Parasitária na Amazônia, Universidade do Estado do Pará e Instituto Evandro Chagas (PPBPA/UEPA/IEC), Belém, Pará, 66087-670, Brazil.
Karla Valéria Batista LimaPrograma de Pós-Graduação em Biologia Parasitária na Amazônia, Universidade do Estado do Pará e Instituto Evandro Chagas (PPBPA/UEPA/IEC), Belém, Pará, 66087-670, Brazil.
Luana Nepomuceno Gondim Costa LimaPrograma de Pós-Graduação em Biologia Parasitária na Amazônia, Universidade do Estado do Pará e Instituto Evandro Chagas (PPBPA/UEPA/IEC), Belém, Pará, 66087-670, Brazil.

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 2CSRD VA 1
6 · The paper itself

Abstract

The common cold is the primary cause of illness in the community, with over 200 viral strains identified, and rhinovirus infections being the most prevalent. Coronavirus Disease 19 (COVID-19) is also a significant cause of severe illness. The burden of acute respiratory infections has a significant impact on the economy, resulting in absenteeism from work and school. Rhinovirus infections can exacerbate asthma and other chronic diseases, leading to hospitalization. The objective of this study is to investigate the factors associated with death and survival in patients hospitalized for rhinovirus in Brazil in 2022. This is a retrospective cohort study using data from the national surveillance of Severe Acute Respiratory Syndrome (SARS) in 2022 in Brazil, with all the norrifications. We analysed and compared clinical and epidemiological factors and outcomes between survivors and deaths in patients hospitalised for rhinovirus. The absolute and relative frequencies were calculated according to the states. Bivariate analysis was performed using chi-squared test and Fisher's exact test, while multivariate analysis was performed using COX regression. Out of 8,130 cases of SARS caused by rhinovirus, 291 (3.58%) resulted in death while 7839 (96.47%) patients survived. The factors associated with death were invasive ventilation (p- < 0.001 HR 4.888 CI 95% 3.816-6.262), bocavirus (p- < 0.001 HR 4.204 CI 95% 2.595-6.812), immunodepression/Immunosuppression (p- < 0.001 HR 2.417 CI 95% 1. 544-3, 786), COVID-19 (p- < 0.001 HR 2.167 CI 95% 1.495-3.142), chronic neurological diseases (p-0.007 HR 1.610 CI 95% 1.137-2.280), abdominal pain (p-0.005 HR 1.734 CI 95% 1.186-2.537), age (p- < 0.001 HR 1.038 CI 95% 1.034-1.042). The survival factors identified in this study were dyspnea (p = 0.005; HR 0.683; CI 95% 0.524-0.889), cough (p < 0.001; HR 0.603; CI 95% 0.472-0.769), and asthma (p = 0.052; HR 0.583; CI 95% 0.339-1.004). Additionally, the study found that receiving a COVID-19 booster dose was also a significant survival factor (p = 0.001; HR 0.570; CI 95% 0.415-0.784). The factors associated with death were similar to those in the literature, and the factors associated with survival were also similar, except for the booster dose of the COVID-19 vaccine, which we didn't find in any studies. Our study is the first to associate the full course of the COVID-19 vaccine with survival in those hospitalized for rhinovirus, regardless of COVID-19 and rhinovirus co-detection.

Indexed as

COVID-19HospitalizationRhinovirusAdolescentAdultAgedBrazilFemaleHumansMaleMiddle AgedPicornaviridae InfectionsRetrospective StudiesSARS-CoV-2Severe Acute Respiratory SyndromeYoung AdultBrazilEpidemiologyHospitalizedOutcomeRhinovirusSevere acute respiratory syndrome

Identifiers

PMID39521845
PMCPMC11550400

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.