ArticleScientific reports2024
Association between serum glucose potassium ratio and mortality in critically ill patients with intracerebral hemorrhage.
Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Electrolyte-derived clinical indices in traumatic brain injury: A narrative review.World journal of methodology · 2026Review
- Glucose-to-potassium ratio has a non-linear J-shaped association with acute kidney injury risk in traumatic brain injury.Scientific reports · 2026Article
- Glucose/potassium ratio and a novel combined model for the differential diagnosis of testicular torsion: a retrospective study.Basic and clinical andrology · 2026Article
- Association between blood urea nitrogen-to-potassium ratio trajectories and MAKE-30 risk in critically patients with non-traumatic subarachnoid hemorrhage.Scientific reports · 2026Article
- Association between serum glucose/potassium ratio and acute kidney injury in patients with traumatic brain injury: based on MIMIC-IV database.Journal of global health · 2026Article
- Comparison of glucose/potassium ratio and revised trauma score in predicting mortality in patients with isolated blunt head trauma.Scientific reports · 2025Article
- U shaped relationship between serum glucose potassium ratio and mortality in critically ill patients with toxic encephalopathy.Scientific reports · 2025Article
- Evaluation of Prognostic Implication of Serum Mixed Lineage Kinase Domain-Like Protein in Acute Primary Supratentorial Intracerebral Hemorrhage: A Multicenter Prospective Cohort Study.Brain and behavior · 2025Article
- Interpretable machine learning model for outcome prediction in patients with aneurysmatic subarachnoid hemorrhage.Critical care (London, England) · 2025Article
- Post-stroke mortality in ICU patients with serum glucose-potassium ratio: an analysis of MIMIC-IV database.Frontiers in neurology · 2025Article
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11 authors.
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Abstract
The effect of serum glucose-to-potassium ratio (GPR) on cerebrovascular diseases has been previously validated. However, the value of the GPR in patients with severe intracerebral hemorrhage (ICH) requiring ICU admission remains unclear. This study aimed to investigate the association between the GPR and the clinical prognosis of critically ill patients with ICH. This study identified patients with severe ICH requiring ICU admission from the Medical Information Mart for Intensive Care (MIMIC-IV) database and divided them into quartiles based on GPR levels. Outcomes included 30-day, 90-day, and 1-year mortality rates. The association between the GPR and clinical outcomes in critically ill patients with ICH was elucidated using Cox proportional hazards regression analysis and restricted cubic splines. In total, 2018 patients (53.8% male), with a median age of 70 years, were enrolled in the study. The 30-day, 90-day, and 1-year mortality rates were 23.9%, 30.1%, and 38.4%, respectively. Per multivariate Cox proportional hazards analysis, an elevated GPR was significantly associated with all-cause mortality. After adjusting for age, sex, Charlson Comorbidity Index, white blood cell count, red blood cell count, platelet count, and Glasgow Coma Scale, patients with an elevated GPR had a higher 30-day mortality (hazard ratio [HR]: 1.32; 95% confidence interval [CI]: 1.22-1.42; P < 0.001), 90-day mortality (HR: 1.27; 95% CI: 1.18-1.37; P < 0.001) and 1-year mortality (HR: 1.22; 95% CI: 1.14-1.31; P < 0.001) when analyzed as a continuous variable. Furthermore, analysis using restricted cubic splines demonstrated a consistent and progressive escalation in the risk of all-cause mortality with an elevated GPR. The GPR was significantly associated with short- and long-term all-cause mortality in critically ill patients with ICH. This finding demonstrates that GPR may be useful in identifying patients with ICH at a high risk of all-cause mortality.
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