Evidence map›Paper›PMID 39521736›Full record

ArticleInternational ophthalmology2024

Evaluation of meibomian gland morphology in keratoconus patients wearing scleral contact lenses.

Ruveyde Bolac, Merve Beyza Yıldız, Elvin Yildiz, Yasemin Un

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Article in International ophthalmology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ruveyde BolacDepartment of Ophthalmology, Haydarpasa Numune Training and Research Hospital, University of Health Sciences, Tibbiye Street. Nu: 23, 34668, Istanbul, Uskudar, Turkey. ruveydebolac@gmail.com.ORCID http://orcid.org/0000-0003-0791-3147
Merve Beyza YıldızDepartment of Ophthalmology, Haydarpasa Numune Training and Research Hospital, University of Health Sciences, Tibbiye Street. Nu: 23, 34668, Istanbul, Uskudar, Turkey.ORCID http://orcid.org/0000-0002-0474-0319
Elvin YildizNorth American Lasik and Eye Surgery Center, 272 Al Wasl Rd, Jumeirah 1, Dubai, United Arab Emirates.ORCID http://orcid.org/0000-0002-4636-1659
Yasemin UnBeyoglu Eye Hospital, Bereketzade Mah. No:8, 34421, Istanbul, Beyoglu, Turkey.ORCID http://orcid.org/0000-0001-6841-3969

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe aimed to evaluate the morphological changes in meibomian glands in keratoconus patients using scleral contact lenses and compare them with keratoconus and healthy controls.

methodsThe study included 34 eyes of 20 patients who were wearing scleral contact lenses due to keratoconus, as well as 31 age- and sex-matched keratoconus controls and 31 healthy controls. Slit-lamp biomicroscopy, non-invasive tear film break-up time assessment, Schirmer I test, meibography, and corneal staining with fluorescein were performed. Subjective symptoms were assessed using the Ocular Surface Disease Index.

resultsIn this study, the lower and upper percentage meibomian gland loss was statistically higher in the scleral contact lens group than in the keratoconus and healthy control groups (p < 0.001 and p = 0.013, respectively). There was a positive correlation between scleral contact lens wear duration and the lower eyelid percentage meibomian gland loss and upper eyelid gland curling scores (rho: 0.396; p = 0.021 and rho: 0.344; p = 0.047, respectively). The lower and upper eyelid percentage meibomian gland loss, and upper eyelid gland curling values were higher, and the Schirmer 1 values were found to be lower in patients who used scleral contact lenses for more than three years than those who wore them less than three years.

conclusionIn patients using scleral contact lenses for more than three years, meibomian gland curling values and percentages of meibomian gland loss in both eyelids are higher.

Indexed as

Contact LensesKeratoconusMeibomian GlandsScleraTearsAdolescentAdultFemaleHumansMaleSlit Lamp MicroscopyYoung AdultKeratoconusMeibographyMeibomian gland curlingMeibomian gland drop outMeibomian gland thickeningMeiboscoreScleral contact lens

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.