Evidence map›Paper›PMID 39521251›Full record

ArticleVirus research2024

Evidence of Zika virus circulation in human and livestock in Chad.

François Chable de la Héronnière, Jonathan Barthelemy, Guy R Takoudjou Dzomo, Fatima Abdelrazakh, Oumaima Djarma, Lucas Auguste, Abderrazzack A Fouda, Chatté Adawaye, Laurent Andreoletti, Mahamat Fayiz Abakar and 3 more

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Article in Virus research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

François Chable de la HéronnièrePathogenesis and Control of Chronic and Emerging Infections (PCCEI), INSERM U1058, University of Montpellier, French Blood Establishment (EFS), Montpellier, France.
Jonathan BarthelemyPathogenesis and Control of Chronic and Emerging Infections (PCCEI), INSERM U1058, University of Montpellier, French Blood Establishment (EFS), Montpellier, France.
Guy R Takoudjou DzomoUniversity Hospital Complex "Le Bon Samaritain", N'Djamena, Chad.
Fatima AbdelrazakhLivestock Research Institute for Development (IRED), N'Djamena, Chad.
Oumaima DjarmaMinistry of Public Health and Solidarity, N'Djamena, Chad.
Lucas AugustePathogenesis and Control of Chronic and Emerging Infections (PCCEI), INSERM U1058, University of Montpellier, French Blood Establishment (EFS), Montpellier, France.
Abderrazzack A FoudaMinistry of Public Health and Solidarity, N'Djamena, Chad; Toumaï University, N'Djamena, Chad.
Chatté AdawayeMinistry of Public Health and Solidarity, N'Djamena, Chad; Faculty of Human Health Sciences, N'Djamena, Chad.
Laurent AndreolettiVirology laboratory, Faculty of Medicine, INSERM U1320, University of Reims Champagne Ardennes, and UHC of Reims, France; Academic Hospital of Reims, Robert Debré, Virology Department, Reims, France.
Mahamat Fayiz AbakarLivestock Research Institute for Development (IRED), N'Djamena, Chad.
Yannick SimoninPathogenesis and Control of Chronic and Emerging Infections (PCCEI), INSERM U1058, University of Montpellier, French Blood Establishment (EFS), Montpellier, France.
Sara SalinasPathogenesis and Control of Chronic and Emerging Infections (PCCEI), INSERM U1058, University of Montpellier, French Blood Establishment (EFS), Montpellier, France.
Franck Jd MennechetPathogenesis and Control of Chronic and Emerging Infections (PCCEI), INSERM U1058, University of Montpellier, French Blood Establishment (EFS), Montpellier, France. Electronic address: franck.mennechet@umontpellier.fr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Zika virus (ZIKV) is a major public health problem worldwide. After several reported outbreaks, the current extent of infections caused by this orthoflavivirus in the Sahel remains to be explored. We investigated the prevalence of neutralizing antibodies against ZIKV in the general population, in HIV-infected individuals and in livestock in Chad using a seroneutralization assay that ensures high specificity level. In this retrospective serological serosurveillance investigation, we estimated the neutralizing seroprevalence to be approximately 26 % (18/69) in healthy Chadian participants and 17 % (16/94) in HIV-infected individuals, with no statistical difference between these two subgroups or genders. In addition, we found an overall ZIKV prevalence of 14 % (8/59) in small ruminants (sheep and goats) living in the Lake Chad Basin area, demonstrating virus circulation in animals. Our pilot study shows for the first-time evidence of ZIKV circulation in humans and in livestock in Chad in close interaction with humans, and highlights the main challenges associated with this virus in Sahelian areas.

Indexed as

Antibodies, ViralGoatsLivestockZika VirusZika Virus InfectionAdolescentAdultAgedAnimalsAntibodies, NeutralizingChadFemaleHIV InfectionsHumansMaleMiddle AgedAntibodies, NeutralizingAntibodies, ViralChadseroneutralization testseroprevalenceZika virus

Identifiers

PMID39521251
PMCPMC11736396

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.