Evidence map›Paper›PMID 39521056›Full record

ArticleJournal of vascular surgery. Venous and lymphatic disorders2025

Residual popliteal vein thrombosis after endovascular treatment of mixed-type lower extremity deep vein thrombosis is relevant to post-thrombotic syndrome.

Jingluo Qiu, Wenjia Ai, Wenduo Gu, Shaomang Lin, Jianbin Xiao, Yinqian Huang, Tao Qiu, Baohui Xu, Zhihui Zhang

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Article in Journal of vascular surgery. Venous and lymphatic disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Jingluo QiuDepartment of Vascular Surgery, The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, China.
Wenjia AiDepartment of Vascular Surgery, The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, China; Department of Surgery, Stanford University School of Medicine, Stanford, CA. Electronic address: think1805@126.com.
Wenduo GuDepartment of Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA.
Shaomang LinDepartment of Vascular Surgery, The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, China.
Jianbin XiaoDepartment of Vascular Surgery, The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, China.
Yinqian HuangDepartment of Vascular Surgery, The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, China.
Tao QiuDepartment of Vascular Surgery, The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, China.
Baohui XuDepartment of Surgery, Stanford University School of Medicine, Stanford, CA.
Zhihui ZhangDepartment of Vascular Surgery, The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivePatients with mixed-type lower extremity deep vein thrombosis (DVT) have a higher incidence of post-thrombotic syndrome (PTS) after endovascular treatment (EVT). This study aimed to identify risk factors associated with PTS in these patients after EVT.

methodsThis retrospective study included patients diagnosed with acute mixed-type lower extremity DVT who underwent EVT between January 2020 and December 2022. Patient assessments were conducted using ultrasound examination and the Villalta scale. Baseline characteristics, management details, and follow-up findings were compared between patients who developed PTS and those who did not at 6 months after EVT. Cox regression and nomogram analyses were performed to identify risk factors associated with the development of PTS.

resultsThe study enrolled 118 patients, of which 103 completed the follow-up. Among them, 24.3% developed post-thrombotic syndrome (PTS) within 6 months. Significant differences between the PTS and non-PTS groups were found concerning residual thrombosis in the popliteal, common femoral, and femoral veins. Multivariate Cox regression analysis indicated that residual popliteal vein thrombosis (RPVT) (hazard ratio [HR], 4.93; 95% confidence interval [CI], 1.61-15.11) and preoperative iliac vein stenosis (HR, 3.21; 95% CI, 1.11-9.33) were significant risk factors for PTS. Additionally, subgroup analysis for preoperative iliac vein stenosis and sensitivity analysis confirmed that RPVT remained a risk factor for PTS (HR, 4.48; 95% CI, 1.27-15.84).

conclusionsOur study demonstrated a positive association between RPVT and PTS in patients with extensive mixed-type lower extremity DVT after EVT. These findings suggest that intensive monitoring and aggressive therapeutic interventions may be required for patients with RPVT to decrease the risk of PTS.

Indexed as

Endovascular ProceduresLower ExtremityPopliteal VeinPostthrombotic SyndromeVenous ThrombosisAdultAgedFemaleHumansMaleMiddle AgedRetrospective StudiesRisk AssessmentRisk FactorsTime FactorsTreatment OutcomeEndovascular treatmentLower extremity deep vein thrombosisPopliteal vein thrombosisPost-thrombotic syndrome

Identifiers

PMID39521056
PMCPMC12014322

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.