Evidence map›Paper›PMID 39520507›Full record

ArticleTechniques in coloproctology2024

Employing innovation to enhance the safety and reliability of restorative surgical techniques for patients with familial adenomatous polyposis at a national referral centre.

B A Alves Martins, A Shamsiddinova, G H T Worley, Y-J Hsu, Victoria Cuthill, M Hawkins, A Sinha, J T Jenkins, D Miskovic, S K Clark and 1 more

Abstract readEvaluation Study
PubMed Publisher
In one paragraph

Article in Techniques in coloproctology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Robotic Intracorporeal Single-Stapled Anastomosis (RiSSA): Indications, Technical Benefits, and Current Limitations.The international journal of medical robotics + computer assisted surgery : MRCAS · 2026
    Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

B A Alves MartinsDepartment of Colorectal Surgery, St Mark's Hospital, London North West University Healthcare NHS Trust, London, UK.
A ShamsiddinovaDepartment of Colorectal Surgery, St Mark's Hospital, London North West University Healthcare NHS Trust, London, UK.
G H T WorleyDepartment of Colorectal Surgery, St Mark's Hospital, London North West University Healthcare NHS Trust, London, UK.
Y-J HsuDepartment of Colorectal Surgery, St Mark's Hospital, London North West University Healthcare NHS Trust, London, UK.
Victoria CuthillSt Mark's Centre for Familial Intestinal Cancer, London North West University Healthcare NHS Trust, London, UK.
M HawkinsSt Mark's Centre for Familial Intestinal Cancer, London North West University Healthcare NHS Trust, London, UK.
A SinhaDepartment of Colorectal Surgery, St Mark's Hospital, London North West University Healthcare NHS Trust, London, UK.
J T JenkinsDepartment of Colorectal Surgery, St Mark's Hospital, London North West University Healthcare NHS Trust, London, UK.
D MiskovicDepartment of Colorectal Surgery, St Mark's Hospital, London North West University Healthcare NHS Trust, London, UK.
S K ClarkDepartment of Colorectal Surgery, St Mark's Hospital, London North West University Healthcare NHS Trust, London, UK.
O D FaizDepartment of Colorectal Surgery, St Mark's Hospital, London North West University Healthcare NHS Trust, London, UK. omar.faiz@nhs.net.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionRestorative proctocolectomy (RPC) and total colectomy with ileorectal anastomosis (TC-IRA) are traditional surgical options for individuals with familial adenomatous polyposis (FAP). Re-appraisal and modification to these techniques, such as near-total colectomy with ileo-distal sigmoid anastomosis (NT-IDSA) and RPC with robotic intracorporeal single-stapled anastomosis (RPC-RiSSA), have been implemented in recent years. This study aimed to evaluate the early postoperative outcomes associated with novel techniques employed in a single centre for restorative surgery in patients with FAP.

methodsA retrospective analysis was conducted using data from patients with FAP who underwent prophylactic restorative surgery between January 2008 and December 2022 at St Mark's Hospital.

resultsTwo hundred fifty-three individuals underwent restorative surgery over the 15-year period; 102/253 (40.3%) underwent TC-IRA, 84 (33.2%) had NT-IDSA, and 67 (26.5%) underwent RPC. Laparoscopic approach was the most common (88.2%) operative access. Seventeen patients (6.7%) underwent robotic operations. For robotic-assisted procedures, no conversions were reported. No anastomotic leaks or 30-day reoperations were reported in the NT-IDSA group compared to 8% (0/84 vs 8/102, p = 0.009) and 11% (0/84 vs 11/102, p = 0.002), respectively, in the TC-IRA group. Regarding RPC, following the introduction of robotic RPC-RiSSA in 2019, no anastomotic leakage was observed compared with 9% (0/11 vs 5/56, p = 0.3) in those undergoing conventional RPC.

conclusionOur institution has transitioned from TC-IRA to NT-IDSA since 2014 and conventional RPC to RPC-RiSSA in 2019. To date, since refinement of the techniques there have been no anastomotic failures amongst these cohorts. The reported results may offer future horizons for patients undergoing similar procedures for alternative colorectal diseases.

Indexed as

Adenomatous Polyposis ColiAnastomosis, SurgicalProctocolectomy, RestorativeRobotic Surgical ProceduresAdolescentAdultColectomyFemaleHumansIleumLaparoscopyMaleMiddle AgedPostoperative ComplicationsRectumReproducibility of ResultsColorectal surgeryFamilial adenomatous polyposisHereditary neoplastic syndromesMinimally invasive surgical proceduresRestorative proctocolectomyRobotic surgical procedures

Identifiers

PMID39520507

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.