Evidence map›Paper›PMID 39520317›Full record

ArticleJournal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG2025

Evaluation of skin cancer screening in Germany - a Microsimulation.

Hannah Baltus, Joachim Hübner, Claudia Garbe, Kristina Hagenström, Maren Rohr, Sandra Hischke, Jobst Augustin, Matthias Augustin, Alexander Katalinic, Nora Eisemann

Abstract read
In one paragraph

Article in Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. A systematic review of microsimulation models for skin cancer.BMC medical informatics and decision making · 2025
    Pooled it
  2. Article
  3. Evaluation of skin cancer screening in Germany - a Microsimulation.Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Hannah BaltusInstitute of Social Medicine and Epidemiology, Lübeck University, Lübeck, Germany.
Joachim HübnerInstitute of Social Medicine and Epidemiology, Lübeck University, Lübeck, Germany.
Claudia GarbeInstitute of Health Services Research in Dermatology and Nursing (IVDP), University Hospital Hamburg-Eppendorf (UKE), Hamburg, Germany.
Kristina HagenströmInstitute of Health Services Research in Dermatology and Nursing (IVDP), University Hospital Hamburg-Eppendorf (UKE), Hamburg, Germany.ORCID 0000-0002-2676-1479
Maren RohrInstitute of Social Medicine and Epidemiology, Lübeck University, Lübeck, Germany.
Sandra HischkeInstitute of Health Services Research in Dermatology and Nursing (IVDP), University Hospital Hamburg-Eppendorf (UKE), Hamburg, Germany.
Jobst AugustinInstitute of Health Services Research in Dermatology and Nursing (IVDP), University Hospital Hamburg-Eppendorf (UKE), Hamburg, Germany.ORCID 0000-0003-1541-2369
Matthias AugustinInstitute of Health Services Research in Dermatology and Nursing (IVDP), University Hospital Hamburg-Eppendorf (UKE), Hamburg, Germany.ORCID 0000-0002-4026-8728
Alexander KatalinicInstitute of Social Medicine and Epidemiology, Lübeck University, Lübeck, Germany.
Nora EisemannInstitute of Social Medicine and Epidemiology, Lübeck University, Lübeck, Germany.

Funding

Innovationsfond 01VSF18002
6 · The paper itself

Abstract

backgroundComprehensive skin cancer screening was introduced in Germany in 2008. It is unclear whether subsequently observed changes in the epidemiology of malignant melanoma (MM), squamous cell carcinoma (SCC) and basal cell carcinoma (BCC) are due to the screening. Simulation models are used to compare different screening scenarios with each other and with observed incidence and mortality trends.

methodsA microsimulation model for MM, SCC, and BCC was programmed and validated separately by sex on skin cancer-specific mortality data. In addition to the currently practiced screening (biennial offer, annual participation probability 15%), triennial screening, screening with increased participation, e.g., via invitation, and no screening were simulated. Incidence, mortality, costs, and life-years gained were simulated for 30 years from the start of screening.

resultsCompared with no screening, mortality is reduced by 13.8% in the simulation with current conditions. This effect occurs in the first years after screening starts before reaching a stable level. More screening allows for further increases in incidence, life-years gained, and costs and decreases in mortality. Comparing simulated and observed effects shows little agreement.

conclusionsThe model is useful for comparing screening scenarios to identify potential optimization opportunities in SCS. Additional, especially risk-adapted, screening scenarios should be investigated.

Indexed as

Computer SimulationEarly Detection of CancerSkin NeoplasmsAdultAgedAged, 80 and overBasal Cell CarcinomaCarcinoma, Squamous CellFemaleGermanyHealth Care CostsHumansIncidenceMaleMass ScreeningMelanomabasal cell carcinomaepidemiologymalignant melanomaNatural History modelsimulation modelsquamous cell carcinoma

Identifiers

PMID39520317
PMCPMC11711918

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.