Evidence map›Paper›PMID 39520083›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2025

Bioactive Self-Assembled Nanoregulator Enhances Hematoma Resolution and Inhibits Neuroinflammation in the Treatment of Intracerebral Hemorrhage.

Wenyan Yu, Chengyuan Che, Yi Yang, Yuzhen Zhao, Junjie Liu, Aibing Chen, Jinjin Shi

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Wenyan YuSchool of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, 450001, China.
Chengyuan CheCollege of Chemical and Pharmaceutical Engineering, Hebei University of Science and Technology, Shijiazhuang, 050018, China.
Yi YangSchool of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, 450001, China.
Yuzhen ZhaoSchool of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, 450001, China.
Junjie LiuSchool of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, 450001, China.
Aibing ChenCollege of Chemical and Pharmaceutical Engineering, Hebei University of Science and Technology, Shijiazhuang, 050018, China.
Jinjin ShiSchool of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, 450001, China.ORCID 0000-0003-1531-7265

Funding

Key Projects of Advantageous Disciplines in Henan Province 222301420011National Natural Science Foundation of China 82073395National Natural Science Foundation of China 82222067Outstanding Youth Foundation of Henan Province Henan 222300420020Program for Innovative Research Team (in Science and Technology) in University of Henan Province 23IRTSTHN025
6 · The paper itself

Abstract

Hematoma and secondary neuroinflammation continue to pose a significant challenge in the clinical treatment of intracerebral hemorrhage (ICH). This study describes a nanoregulator formed through the self-assembly of Mg

Indexed as

Cerebral HemorrhageDisease Models, AnimalHematomaNeuroinflammatory DiseasesAnimalsDNA, CatalyticMagnesiumMaleMiceMicrogliaRatsSignal TransductionDNA, CatalyticMagnesiumdrug deliveryhematoma clearanceintracerebral hemorrhage therapymicroglia polarizationnanotechnology

Identifiers

PMID39520083
PMCPMC11714160

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.