ArticlePlants (Basel, Switzerland)2024
Melatonin Ameliorates Cadmium Toxicity in Tobacco Seedlings by Depriving Its Bioaccumulation, Enhancing Photosynthetic Activity and Antioxidant Gene Expression.
Article in Plants (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Ascorbic and citric acids mitigate cadmium stress and reduce metal accumulation in spinach grown in alkaline calcareous soil.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2026Article
- Co-application of biochar and melatonin enhances rice resilience to combined lead and microplastics stress via modulating antioxidant defense, hormonal regulation, gene expression, and soil quality.BMC plant biology · 2026Article
- Role of Acacia bark biochar in the growth of Ocimum basilicum L. under cadmium stress.Biodegradation · 2026Article
- Reclaiming multi-contaminated soil: melatonin alleviates cadmium and microplastic toxicity to restore rice growth and yield.RSC advances · 2026Article
- Cytological basis and key metabolite profiling of fresh tobacco leaves with different oiliness indices in Yunyan 87.Frontiers in plant science · 2026Article
- Molecular insights into melatonin-mediated stress tolerance in rice.Plant cell reports · 2025Review
- Integrative biochar and melatonin application mitigates lead toxicity in rice by modulating antioxidant activities and iron plaque formation and downregulating the expression of metal uptake genes.Frontiers in plant science · 2025Article
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Authors and funding
9 authors.
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Abstract
Soil remediation for cadmium (Cd) toxicity is essential for successful tobacco cultivation and production. Melatonin application can relieve heavy metal stress and promote plant growth; however, it remains somewhat unclear whether melatonin supplementation can remediate the effects of Cd toxicity on the growth and development of tobacco seedlings. Herein, we evaluated the effect of soil-applied melatonin on Cd accumulation in tobacco seedlings, as well as the responses in growth, physiological and biochemical parameters, and the expression of stress-responsive genes. Our results demonstrate that melatonin application mitigated Cd stress in tobacco, and thus promoted plant growth. It increased root fresh weight, dry weight, shoot fresh weight and dry weight by 58.40%, 163.80%, 34.70% and 84.09%, respectively, compared to the control. Physiological analyses also showed significant differences in photosynthetic rate and pigment formation among the treatments, with the highest improvements recorded for melatonin application. In addition, melatonin application alleviated Cd-induced oxidative damage by reducing MDA content and enhancing the activities of enzymatic antioxidants (CAT, SOD, POD and APX) as well as non-enzymatic antioxidants (GSH and AsA). Moreover, confocal microscopic imaging confirmed the effectiveness of melatonin application in sustaining cell integrity under Cd stress. Scanning Electron Microscopy (SEM) observations illustrated the alleviative role of melatonin on stomata and ultrastructural features under Cd toxicity. The qRT-PCR analysis revealed that melatonin application upregulated the expression of photosynthetic and antioxidant-related genes, including
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