A Novel Near-Infrared Tricyanofuran-Based Fluorophore Probe for Polarity Detection and LD Imaging.

Zhaojia Hang, Shengmeng Jiang, Zhitong Wu, Jin Gong, Lizhi Zhang

Abstract read

In one paragraph

Article in Molecules (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Development of 2,1,3-Benzothiadiazole-Based Room-Temperature Fluorescent Nematic Liquid Crystals.Molecules (Basel, Switzerland) · 2025
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zhaojia HangCollege of Science, Gansu Agricultural University, Lanzhou 730070, China.

Shengmeng JiangSchool of Chemistry and Chemical Engineering, Shandong University of Technology, Zibo 255000, China.

Zhitong WuSchool of Chemistry and Chemical Engineering, Shandong University of Technology, Zibo 255000, China.

Jin GongSchool of Pharmacy, Shandong Second Medical University, Weifang 261053, China.

Lizhi ZhangSchool of Chemistry and Chemical Engineering, Shandong University of Technology, Zibo 255000, China.ORCID 0000-0002-8036-7309

Funding

National Natural Science Foundation of China 22301169Natural Science Foundation of Shandong Province, China ZR2022QH060

6 · The paper itself

Abstract

In this paper, LD-TCF, a targeting probe for lipid droplets (LDs) with a near-infrared emission wavelength and large Stokes shift, was fabricated for polarity detection by assembling a donor-π-acceptor (D-π-A) molecule with typical twisted intramolecular charge transfer (TICT) characteristics. Surprisingly, the fluorescence emission wavelength of the newly constructed probe LD-TCF was stretched to 703 nm, and the Stokes shift was amplified to 126 nm. Furthermore, LD-TCF could specifically answer the change in polarity efficiently and did not experience interference from other biologically active materials. Importantly, LD-TCF exhibited the ability to target lipid droplets, providing valuable insights for the early diagnosis and tracking of pathophysiological processes underlying LD polarity.

Indexed as

Fluorescent DyesLipid DropletsFuransHumansFluorescent DyesFuranscell imaginglarge stokes shiftlipid dropletsnear-infraredpolarity

Identifiers

PMID39519710

DOI10.3390/molecules29215069

PMCPMC11547870

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.