Evidence map›Paper›PMID 39519652›Full record

ReviewMolecules (Basel, Switzerland)2024

DNA Catalysis: Design, Function, and Optimization.

Rebecca L Stratton, Bishal Pokhrel, Bryce Smith, Adeola Adeyemi, Ananta Dhakal, Hao Shen

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rebecca L StrattonDepartment of Chemistry and Biochemistry, Kent State University, Kent, OH 44242, USA.ORCID 0009-0001-8005-7327
Bishal PokhrelDepartment of Chemistry and Biochemistry, Kent State University, Kent, OH 44242, USA.ORCID 0000-0003-4405-6957
Bryce SmithDepartment of Chemistry and Biochemistry, Kent State University, Kent, OH 44242, USA.
Adeola AdeyemiDepartment of Chemistry and Biochemistry, Kent State University, Kent, OH 44242, USA.ORCID 0009-0001-3492-9083
Ananta DhakalDepartment of Chemistry and Biochemistry, Kent State University, Kent, OH 44242, USA.
Hao ShenDepartment of Chemistry and Biochemistry, Kent State University, Kent, OH 44242, USA.ORCID 0000-0002-2798-5861

Funding

National Science Foundation CHE2247709
6 · The paper itself

Abstract

Catalytic DNA has gained significant attention in recent decades as a highly efficient and tunable catalyst, thanks to its flexible structures, exceptional specificity, and ease of optimization. Despite being composed of just four monomers, DNA's complex conformational intricacies enable a wide range of nuanced functions, including scaffolding, electrocatalysis, enantioselectivity, and mechano-electro spin coupling. DNA catalysts, ranging from traditional DNAzymes to innovative DNAzyme hybrids, highlight the remarkable potential of DNA in catalysis. Recent advancements in spectroscopic techniques have deepened our mechanistic understanding of catalytic DNA, paving the way for rational structural optimization. This review will summarize the latest studies on the performance and optimization of traditional DNAzymes and provide an in-depth analysis of DNAzyme hybrid catalysts and their unique and promising properties.

Indexed as

DNA, CatalyticCatalysisDNANucleic Acid ConformationDNADNA, CatalyticdesignDNA catalysisDNA-nanoparticle hybridDNAzymefunctionoptimization

Identifiers

PMID39519652
PMCPMC11547689

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.