Evidence map›Paper›PMID 39519585›Full record

ArticleNutrients2024

Effect of Oral Administration of Collagen Peptide OG-5 on Advanced Atherosclerosis Development in ApoE

Yijie Yang, Bo Li

Abstract read
In one paragraph

Article in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Yijie YangDepartment of Nutrition and Health, China Agricultural University, Beijing 100193, China.
Bo LiCollege of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, China.ORCID 0000-0003-2726-2900

Funding

China Agriculture Research System of MOF and MARA CARS-45the National Key Research and Development Program of China 2018YFD0901102
6 · The paper itself

Abstract

BACKGROUND/

objectivesAtherosclerosis is a chronic inflammatory disease of the arterial wall, which involves multiple cell types. Peptide OG-5 is identified from collagen hydrolysates derived from

methodsIn this study, the ApoE-/- mice were employed to establish advanced atherosclerosis model to investigate the treatment effect of peptide OG-5.

resultsThe results showed that oral administration of OG-5 at a dosage of 150 mg/kg bw resulted in a 30% reduction in the aortic plaque formation area in ApoE

conclusionThe present results demonstrate the potential efficacy of peptide OG-5 as a promising agent for intervention in anti-atherogenesis strategies.

Indexed as

Apolipoproteins EAtherosclerosisCollagenAdministration, OralAnimalsAortaCaco-2 CellsDisease Models, AnimalHumansMaleMiceMice, Inbred C57BLMice, KnockoutPeptidesPlaque, AtheroscleroticApolipoproteins ECollagenPeptidesatherosclerosiscollagen peptidevascular smooth muscle cells

Identifiers

PMID39519585
PMCPMC11547735

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.