Evidence map›Paper›PMID 39519548›Full record

ArticleNutrients2024

Weight Loss, Pathological Changes, and Inflammatory Effects from a Short-Term Ketogenic Diet in Overweight and Obese Men with Untreated Prostate Cancer on Active Surveillance.

Adeel Kaiser, Mohummad M Siddiqui, Jason Bosley-Smith, Shu Wang, Joseph Aryankalayil, Mark V Mishra, Alice S Ryan, Christopher R D'Adamo

Abstract read
In one paragraph

Article in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
  4. Review
  5. Review
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  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Adeel KaiserDepartment of Radiation Oncology, University of Maryland School of Medicine, Baltimore, MD 21201, USA.ORCID 0000-0003-1962-8351
Mohummad M SiddiquiDivision of Urology, Department of Surgery, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
Jason Bosley-SmithCenter for Integrative Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
Shu WangDivision of Urology, Department of Surgery, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
Joseph AryankalayilDepartment of Radiation Oncology, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
Mark V MishraDepartment of Radiation Oncology, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
Alice S RyanDepartment of Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
Christopher R D'AdamoDepartment of Family and Community Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA.ORCID 0000-0002-2415-8158

Funding

University of Maryland Claude D. Pepper Older Americans Independence Center (UM-OAIC)P30AG028747 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI ALICE S. RYAN · 2006 to 2026
$28.9M
Research BaseP30DK072488 · NIDDK · UNIVERSITY OF MARYLAND BALTIMORE · PI MITCHELL, BRAXTON D, TAYLOR, SIMEON I. · 2005 to 2019
$17.3M
NIA NIH HHS P30 AG028747RRD VA IK6 RX003977This clinical trial was grant supported by Mid-Atlantic Nutrition and Obesity Research Center through the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) P30-DK072488.
6 · The paper itself

Abstract

BACKGROUND AND

aimsActive Surveillance (AS) is a favored strategy for the management of indolent prostate cancers (PCs). Overweight and obese men harbor an increased risk of cancer progression during AS. We aim to prospectively evaluate the feasibility and outcomes of a ketogenic diet (KD) weight-loss intervention in overweight men with PC. MATERIALS AND

methodsMen with PC and a BMI > 25 kg/m

resultsTen AS patients aged 62.1 (±5.4) years were enrolled with an average BMI of 31.7 kg/m

conclusionsShort-term KD interventions for BMI reduction are feasible in men undergoing AS for PC and may result in favorable pathological effects without inflammatory marker changes. Larger studies with longer follow-up are needed to explore whether KD-induced weight loss can improve clinical outcomes with AS in PC.

Indexed as

Diet, KetogenicObesityOverweightProstatic NeoplasmsWeight LossAgedBody Mass IndexFeasibility StudiesHumansInflammationKetonesMaleMiddle AgedProspective StudiesProstate-Specific AntigenKetonesProstate-Specific Antigenactive surveillanceinflammationketogenic dietobesityoverweightprostate cancer

Identifiers

PMID39519548
PMCPMC11547181

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.