Evidence map›Paper›PMID 39519510›Full record

ArticleNutrients2024

Low Caloric Intake Confers Cardiovascular Protection and Improves Functional Capacity Without Affecting Immunological Response in Sedentary Older Adults.

Meiry de Souza Moura-Maia, Boris Brill, Rosa Helena Ramos Paula-Vieira, Nycole Vieira Ramos-Gomes, Dobroslav Melamed, Anamei Silva-Reis, Eduarda Teodora Rachid Wolpp, Naiara Nadia Moreira-Silva, Yanesko Fernandes Bella, Rodolfo P Vieira

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Meiry de Souza Moura-MaiaLaboratory of Pulmonary and Exercise Immunology, Universidade Evangélica de Goiás (UniEvangélica), Avenida Universitária Km 3,5, Anápolis 75083-515, GO, Brazil.
Boris BrillLeniado Medical Center, Divrei Khayim St. 16, Nethanya 4244916, Israel.
Rosa Helena Ramos Paula-VieiraLaboratory of Pulmonary and Exercise Immunology, Universidade Evangélica de Goiás (UniEvangélica), Avenida Universitária Km 3,5, Anápolis 75083-515, GO, Brazil.
Nycole Vieira Ramos-GomesLaboratory of Pulmonary and Exercise Immunology, Universidade Evangélica de Goiás (UniEvangélica), Avenida Universitária Km 3,5, Anápolis 75083-515, GO, Brazil.
Dobroslav MelamedLibi Pharm, Department of Research and Development, Ben Gurion 70, Rechovot 7639461, Israel.
Anamei Silva-ReisLaboratory of Pulmonary and Exercise Immunology, Universidade Evangélica de Goiás (UniEvangélica), Avenida Universitária Km 3,5, Anápolis 75083-515, GO, Brazil.ORCID 0000-0002-4446-4320
Eduarda Teodora Rachid WolppLaboratory of Pulmonary and Exercise Immunology, Universidade Evangélica de Goiás (UniEvangélica), Avenida Universitária Km 3,5, Anápolis 75083-515, GO, Brazil.ORCID 0009-0004-2792-3312
Naiara Nadia Moreira-SilvaLaboratory of Pulmonary and Exercise Immunology, Universidade Evangélica de Goiás (UniEvangélica), Avenida Universitária Km 3,5, Anápolis 75083-515, GO, Brazil.
Yanesko Fernandes BellaHeroes Science Institute, Rua Ezequiel Freire, 51, Room 107, São Paulo 02034-000, SP, Brazil.
Rodolfo P VieiraLaboratory of Pulmonary and Exercise Immunology, Universidade Evangélica de Goiás (UniEvangélica), Avenida Universitária Km 3,5, Anápolis 75083-515, GO, Brazil.ORCID 0000-0001-6379-1143

Funding

Fundação de Amparo à Pesquisa do Estado de São Paulo #2012/15165-2Fundação de Apoio a Pesquisa do Estado de Goiás #202310267000648
6 · The paper itself

Abstract

backgroundAging is characterized by a decline in the cardiovascular hemodynamic response, which may be aggravated by undernutrition. However, no study has evaluated whether low caloric intake may affect cardiovascular hemodynamics and its possible relation with functional capacity and immune response in older adults.

methodsSixty-one older adults of both genders were enrolled in this study and were classified as normocaloric (n = 18) and hypocaloric (n = 43). All volunteers were evaluated for cardiovascular hemodynamics using impedance cardiography (PhysioFlow

resultsThe hypocaloric group presented impaired functional capacity, measured by a reduced number of sit-to-stand repetitions (

conclusionsA long-term hypocaloric diet in eutrophic older adults' resulted in an enhanced cardiovascular hemodynamic response but was associated with reduced functional capacity without changes in the immune response.

Indexed as

HemodynamicsAgedAgingCaloric RestrictionCardiovascular DiseasesEnergy IntakeFemaleGlucuronidaseHumansInterleukin-10Interleukin-6Klotho ProteinsMaleMiddle AgedSedentary BehaviorTumor Necrosis Factor-alphaGlucuronidaseInterleukin-10Interleukin-6Klotho ProteinsTumor Necrosis Factor-alphaagingcaloric deficiencycardiac functioncardiovascular hemodynamichypocaloric diet

Identifiers

PMID39519510
PMCPMC11547299

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.