Evidence map›Paper›PMID 39519482›Full record

SynthesisNutrients2024

Is Serum Vitamin D Associated with Depression or Anxiety in Ante- and Postnatal Adult Women? A Systematic Review with Meta-Analysis.

Luis Otávio Lobo Centeno, Matheus Dos Santos Fernandez, Francisco Wilker Mustafa Gomes Muniz, Aline Longoni, Adriano Martimbianco de Assis

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Vitamin D and Vitamin BDiseases (Basel, Switzerland) · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Luis Otávio Lobo CentenoGraduate Program in Health and Behavior, Catholic University of Pelotas (UCPel), Pelotas 96015-560, RS, Brazil.
Matheus Dos Santos FernandezGraduate Program in Dentistry, Federal University of Pelotas (UFPel), Pelotas 96015-560, RS, Brazil.ORCID 0000-0001-7781-3083
Francisco Wilker Mustafa Gomes MunizGraduate Program in Dentistry, Federal University of Pelotas (UFPel), Pelotas 96015-560, RS, Brazil.ORCID 0000-0002-3945-1752
Aline LongoniGraduate Program in Health and Behavior, Catholic University of Pelotas (UCPel), Pelotas 96015-560, RS, Brazil.
Adriano Martimbianco de AssisGraduate Program in Health and Behavior, Catholic University of Pelotas (UCPel), Pelotas 96015-560, RS, Brazil.ORCID 0000-0002-1953-7831

Funding

Coordenação de Aperfeicoamento de Pessoal de Nível Superior 88881.710320/2022-01Instituto Nacional de Ciência e Tecnologia em Excitotoxicidade e Neuroproteção 465671/2014-4National Council for Scientific and Technological Development 404804/2021-7
6 · The paper itself

Abstract

BACKGROUND/

objectivesTo collect evidence from studies that explored the associations between serum vitamin D (25[OH]D) concentrations/status and the presence of depressive/anxiety symptoms in the ante- and/or postnatal periods (PROSPERO-CRD42023390895).

methodsStudies that assessed serum 25[OH]D concentrations in adult women during the ante/postnatal periods and those that used valid instruments to identify the experience/severity of depressive/anxiety symptoms were included. Independent researchers performed the identification/selection of studies, data extraction, risk of bias (RoB) assessment, and bibliometric analysis steps.

resultsOf the total of 6769 eligible records, 15 cohort studies [high (

conclusionsBased on very low/low-quality evidence, it was observed that reduced serum 25[OH]D concentrations in the ante- and postnatal period are associated with the presence of ante- and postnatal depressive symptoms, respectively. Low/deficient antenatal serum 25[OH]D concentrations may not be related to the presence of anxiety symptoms before childbirth. Well-designed longitudinal studies are needed to explore the estimated pooled effect of these associations.

Indexed as

AnxietyDepressionVitamin DAdultDepression, PostpartumFemaleHumansPostpartum PeriodPregnancyPregnancy ComplicationsVitamin D Deficiency25-hydroxyvitamin DVitamin Danxietydepressionpostpartumpregnancypuerperal cyclevitamin D

Identifiers

PMID39519482
PMCPMC11547481

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.