The Effect of Pre-Exercise Caffeine and Glucose Ingestion on Endurance Capacity in Hypoxia: A Double-Blind Crossover Trial.

Chih-Hui Chiu, Chung-Chih Chen, Ajmol Ali, Shey-Lin Wu, Ching-Lin Wu

Abstract readRandomized Controlled Trial

In one paragraph

Trial report in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Effects of WatchingCardiovascular & hematological disorders drug targets · 2025
Trial

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Chih-Hui ChiuGraduate Program in Department of Exercise Health Science, National Taiwan University of Sport, Taichung 404401, Taiwan.ORCID 0000-0002-0739-874X

Chung-Chih ChenGraduate Institute of Sports and Health Management, National Chung Hsing University, Taichung 402202, Taiwan.

Ajmol AliSchool of Sport, Exercise and Nutrition, Massey University, Auckland 0745, New Zealand.ORCID 0000-0002-6093-1435

Shey-Lin WuNeurological Department, Show Chwan Memorial Hospital, Changhua 500209, Taiwan.

Ching-Lin WuGraduate Institute of Sports and Health Management, National Chung Hsing University, Taichung 402202, Taiwan.ORCID 0000-0002-6676-9344

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The impact of caffeine and glucose supplementation in a hypoxic environment on endurance exercise performance remains inconclusive. The current study examined the effect of pre-exercise carbohydrate and caffeine supplementation on endurance exercise performance in an acute hypoxic environment. Eight healthy active young males participated in this double-blind, within-subjects crossover study. Participants ingested the test drink 60 min before exercising at 50% Wmax for 90 min on a cycle ergometer (fatiguing preload); there followed an endurance performance test at 85% Wmax until exhaustion in a hypoxic chamber (~15%O

Indexed as

CaffeineCross-Over StudiesGlucoseHypoxiaPhysical EnduranceAdultBlood GlucoseDietary SupplementsDouble-Blind MethodExerciseHumansMaleYoung AdultBlood GlucoseCaffeineGlucoseendurance performancefat oxidationglycogenhypoxia

Identifiers

PMID39519456

DOI10.3390/nu16213624

PMCPMC11547503

What OpenQuestion holds

Textmetadata

LicenceCC BY

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.