Evidence map›Paper›PMID 39519448›Full record

ReviewNutrients2024

The Role of the Gut Microbiome in Urinary Tract Infections: A Narrative Review.

Zaryan Safdar Iqbal, Sofie Ingdam Halkjær, Khaled Saoud Ali Ghathian, Julie Elm Heintz, Andreas Munk Petersen

Abstract readReview
In one paragraph

Review in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Review
  9. Commentary:Frontiers in cellular and infection microbiology · 2025
    Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zaryan Safdar IqbalGastrounit, Medical Section, Copenhagen University Hospital-Amager and Hvidovre, 2650 Hvidovre, Denmark.ORCID 0009-0000-6273-303X
Sofie Ingdam HalkjærGastrounit, Medical Section, Copenhagen University Hospital-Amager and Hvidovre, 2650 Hvidovre, Denmark.ORCID 0000-0001-7518-4252
Khaled Saoud Ali GhathianDepartment of Clinical Microbiology, Copenhagen University Hospital-Amager and Hvidovre, 2650 Hvidovre, Denmark.ORCID 0000-0003-0964-4059
Julie Elm HeintzDepartment of Clinical Microbiology, Copenhagen University Hospital-Amager and Hvidovre, 2650 Hvidovre, Denmark.
Andreas Munk PetersenGastrounit, Medical Section, Copenhagen University Hospital-Amager and Hvidovre, 2650 Hvidovre, Denmark.ORCID 0000-0003-0531-0553

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesUrinary tract infections (UTIs) represent a substantial health concern worldwide. Although it is known that the gut can act as a reservoir for UTI-causing pathogens, the exact role of the gut microbiome in developing UTIs remains unclear. This review aims to investigate the link between the gut microbiome and UTIs and whether gut dysbiosis increases the risk of getting a UTI.

methodsTo find relevant studies, a search was conducted across three databases, PubMed, EMBASE and Cochrane Library. Only records that directly described the association between the gut microbiome and UTIs were included in this review.

resultsOf the numerous studies retrieved, eight studies met the pre-set criteria and were selected for the review. The findings suggest several potential ways in which gut dysbiosis might enhance UTI susceptibility. A low gut microbiome diversity, a reduced level of bacteria involved in short-chain fatty acid (SCFA) production and a high abundance of

conclusionsResearch on the link between the gut microbiome and UTIs is limited, and further studies need to be carried out to substantiate this relationship, as this can bring attention to finding improved and more relevant treatment for UTIs.

Indexed as

DysbiosisGastrointestinal MicrobiomeUrinary Tract InfectionsEscherichia coliFatty Acids, VolatileFemaleHumansMaleFatty Acids, VolatiledysbiosisEscherichia coligut microbiomeshort-chain fatty acidsurinary tract infection

Identifiers

PMID39519448
PMCPMC11547363

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.