Evidence map›Paper›PMID 39519400›Full record

ArticleInternational journal of molecular sciences2024

The Association of

Tomas Jakstas, Agne Bartnykaite, Evaldas Padervinskis, Aurelija Vegiene, Elona Juozaityte, Virgilijus Uloza, Rasa Ugenskiene

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Tomas JakstasDepartment of Otorhinolaryngology, Lithuanian University of Health Sciences, 50161 Kaunas, Lithuania.ORCID 0000-0002-5041-1268
Agne BartnykaiteOncology Institute, Lithuanian University of Health Sciences, 50161 Kaunas, Lithuania.ORCID 0000-0002-6317-2032
Evaldas PadervinskisDepartment of Otorhinolaryngology, Lithuanian University of Health Sciences, 50161 Kaunas, Lithuania.
Aurelija VegieneDepartment of Otorhinolaryngology, Lithuanian University of Health Sciences, 50161 Kaunas, Lithuania.
Elona JuozaityteOncology Institute, Lithuanian University of Health Sciences, 50161 Kaunas, Lithuania.ORCID 0000-0001-6695-7786
Virgilijus UlozaDepartment of Otorhinolaryngology, Lithuanian University of Health Sciences, 50161 Kaunas, Lithuania.ORCID 0000-0002-8985-5472
Rasa UgenskieneOncology Research Laboratory, Oncology Institute, Lithuanian University of Health Sciences, 50161 Kaunas, Lithuania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Head and neck cancer is the seventh leading cancer diagnosis worldwide. One of the most common cancers in the head and neck region is laryngeal cancer. In past years, the incidence of laryngeal squamous cell carcinoma has risen by 23%, and despite progress in treatment modalities, the survival rate has not changed. It is well known that genetic alterations may contribute to individuals' susceptibility to cancer. Research of genetic alterations, such as single nucleotide polymorphisms, is essential to understanding carcinogenesis and susceptibility of laryngeal squamous cell carcinoma. A total of 200 LSCC patients and 200 controls were included in this retrospective case-control study; both groups were matched by age and sex. In the present study, we analyzed six SNPs in genes essential for apoptosis regulation:

Indexed as

bcl-2-Associated X ProteinGenetic Predisposition to DiseaseLaryngeal NeoplasmsPolymorphism, Single NucleotideProto-Oncogene Proteins c-bcl-2Tumor Suppressor Protein p53AgedCarcinoma, Squamous CellCase-Control StudiesFemaleGenotypeHumansMaleMiddle AgedRetrospective StudiesSquamous Cell Carcinoma of Head and NeckBAX protein, humanbcl-2-Associated X ProteinBCL2 protein, humanPMAIP1 protein, humanProto-Oncogene Proteins c-bcl-2TP53 protein, humanTumor Suppressor Protein p53BAXBCL2laryngeal squamous cell carcinomaNOXASNPTP53

Identifiers

PMID39519400
PMCPMC11546907

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.