ReviewInternational journal of molecular sciences2024
Space Travel: The Radiation and Microgravity Effects on the Cardiovascular System.
Review in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed.
- CB001 bioactive compounds mitigate intestinal immune dysregulation induced by simulated microgravity and radiation via B cells modulation.Pharmaceutical biology · 2026Article
- Robust Polyimide/Graphene Composites as Electrically Functional Materials for Space-Compatible Biomedical Applications.Polymers · 2026Article
- Beyond Earth: Recent Advancements in Microgravity Biomedical and Genetic Research in Saudi Arabia.International journal of molecular sciences · 2026Review
- Spaceflight multi-omics reveals vulnerabilities of human germ cell development.Science advances · 2026Article
- Cardiovascular risks and hazards associated with deep space exploration.Communications medicine · 2026Review
- Mechanisms of Mechanical Stress-Induced Vascular Remodeling via the Lactate-PKM2 Axis and Implications for Microgravity Adaptation.International journal of molecular sciences · 2026Article
- Anticoagulants for the prevention and treatment of venous thromboembolism in humans exposed to microgravity: A hybrid systematic and narrative review.American heart journal plus : cardiology research and practice · 2026Review
- Space radiation health risks to hematopoietic, neural, and gastrointestinal systems in astronauts.Frontiers in public health · 2026Review
- Ovarian Reproductive and Endocrine Function Investigated in Microgravity Environment.Methods in molecular biology (Clifton, N.J.) · 2026Article
- Review of microgravity's impact on cardiovascular and nervous systems in space exploration.NPJ microgravity · 2025Review
- Special Issue "Current Research for Heart Disease Biology and Therapeutics: 2nd Edition".International journal of molecular sciences · 2025Article
- [Risks, mechanisms, and prevention strategies for cerebrovascular diseases in lunar astronauts under deep].Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2025Review
- Blood flow restriction training in microgravity: a review of multisystem physiological benefits and implementation challenges for long-duration space missions.NPJ microgravity · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Space flight modulates the functions of the cardiovascular system. The exposure to space conditions can alter the cerebral blood flow, as well as the venous return. Anemia, cardiac output changes, and increased activity of the sympathetic nervous system can also be seen. Understanding cardiac changes prepares astronauts for both better in-flight adaptations and long-term protection against cardiovascular diseases. The heart could undergo radio-degenerative effects when exposed to space radiation, increasing the risk of cardiovascular diseases in the long run. A high frequency of arrhythmias, such as ventricular/atrial premature complexes, have been reported during the Gemini and Apollo missions. Additionally, microgravity can lead to progressive degeneration of the myocytes and muscle atrophy with altered gene expression and calcium handling, along with impaired contractility. This review summarizes the potential cardiovascular effects of spaceflight and prevention measures.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.