Evidence map›Paper›PMID 39519338›Full record

ArticleInternational journal of molecular sciences2024

Maximilian M Menger, Rouven Speicher, Sandra Hans, Tina Histing, Moses K D El Kayali, Sabrina Ehnert, Michael D Menger, Emmanuel Ampofo, Selina Wrublewsky, Matthias W Laschke

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Maximilian M MengerDepartment of Trauma and Reconstructive Surgery, BG Trauma Center Tuebingen, Eberhard Karls University Tuebingen, 72076 Tuebingen, Germany.ORCID 0000-0002-1261-9877
Rouven SpeicherInstitute for Clinical and Experimental Surgery, Saarland University, 66421 Homburg, Germany.
Sandra HansInstitute for Clinical and Experimental Surgery, Saarland University, 66421 Homburg, Germany.
Tina HistingDepartment of Trauma and Reconstructive Surgery, BG Trauma Center Tuebingen, Eberhard Karls University Tuebingen, 72076 Tuebingen, Germany.
Moses K D El KayaliInstitute for Clinical and Experimental Surgery, Saarland University, 66421 Homburg, Germany.
Sabrina EhnertDepartment of Trauma and Reconstructive Surgery, BG Trauma Center Tuebingen, Siegfried Weller Institute for Trauma Research, Eberhard Karls University Tuebingen, 72076 Tuebingen, Germany； sehnert@bgu-tuebingen.de .ORCID 0000-0003-4347-1702
Michael D MengerInstitute for Clinical and Experimental Surgery, Saarland University, 66421 Homburg, Germany.
Emmanuel AmpofoInstitute for Clinical and Experimental Surgery, Saarland University, 66421 Homburg, Germany.ORCID 0000-0002-1886-5657
Selina WrublewskyInstitute for Clinical and Experimental Surgery, Saarland University, 66421 Homburg, Germany.ORCID 0009-0004-9134-8463
Matthias W LaschkeInstitute for Clinical and Experimental Surgery, Saarland University, 66421 Homburg, Germany.ORCID 0000-0002-7847-8456

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammation has been recognized as major factor for successful bone regeneration. On the other hand, a prolonged or overshooting inflammatory response can also cause fracture healing failure. The nucleotide-binding oligomerization domain (NOD)-like receptor protein (NLRP)3 inflammasome plays a crucial role in inflammatory cytokine production. However, its role during fracture repair remains elusive. We investigated the effects of

Indexed as

Femoral FracturesFracture HealingMice, KnockoutNLR Family, Pyrin Domain-Containing 3 ProteinAnimalsBony CallusInflammasomesMacrophagesMaleMiceMice, Inbred C57BLVascular Endothelial Growth Factor AInflammasomesNLR Family, Pyrin Domain-Containing 3 ProteinNlrp3 protein, mouseVascular Endothelial Growth Factor AAIM2angiogenesisbone regenerationfracture healinginflammasomeNLRP3VEGF

Identifiers

PMID39519338
PMCPMC11546854

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.