Evidence map›Paper›PMID 39519260›Full record

ArticleInternational journal of molecular sciences2024

Kinin Receptors B1 and B2 Mediate Breast Cancer Cell Migration and Invasion by Activating the FAK-Src Axis.

Felipe González-Turén, Lorena Lobos-González, Alexander Riquelme-Herrera, Andrés Ibacache, Luis Meza Ulloa, Alexandra Droguett, Camila Alveal, Bastián Carrillo, Javiera Gutiérrez, Pamela Ehrenfeld and 1 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Felipe González-TurénSchool of Nursing, Faculty of Health Sciences, Universidad Bernardo O'Higgins, Santiago 8370854, Chile.
Lorena Lobos-GonzálezLaboratory of Cellular Communication, Program of Cell and Molecular Biology, Biomedical Sciences Institute (ICBM), Faculty of Medicine, Universidad de Chile, Santiago 8370854, Chile.
Alexander Riquelme-HerreraCentro Integrativo de Biología y Química Aplicada (CIBQA), Faculty of Health Sciences, Universidad Bernardo O'Higgins, Santiago 8370854, Chile.
Andrés IbacacheLaboratory of Molecular Design, Faculty of Biological Sciences, Pontificia Universidad Católica de Chile, Santiago 8370854, Chile.ORCID 0000-0002-5803-1200
Luis Meza UlloaSchool of Medical Technology, Faculty of Health Sciences, Universidad Bernardo O'Higgins, Santiago 8370854, Chile.
Alexandra DroguettSchool of Medical Technology, Faculty of Health Sciences, Universidad Bernardo O'Higgins, Santiago 8370854, Chile.
Camila AlvealSchool of Medical Technology, Faculty of Health Sciences, Universidad Bernardo O'Higgins, Santiago 8370854, Chile.
Bastián CarrilloSchool of Medical Technology, Faculty of Health Sciences, Universidad Bernardo O'Higgins, Santiago 8370854, Chile.
Javiera GutiérrezSchool of Medical Technology, Faculty of Health Sciences, Universidad Bernardo O'Higgins, Santiago 8370854, Chile.
Pamela EhrenfeldLaboratory of Cellular Pathology, Institute of Anatomy, Histology & Pathology, Faculty of Medicine, Universidad Austral de Chile, Valdivia 5110566, Chile.ORCID 0000-0002-2519-7570
Areli Cárdenas-OyarzoSchool of Obstetrics and Puericulture, Faculty of Medical Sciences, Universidad Bernardo O'Higgins, Santiago 8370854, Chile.ORCID 0009-0006-6759-6306

Funding

FONDECYT 11220657
6 · The paper itself

Abstract

Kinin receptors B1 and B2 are involved in migration and invasion in gastric, glioma, and cervical cancer cells, among others. However, the role of kinin receptors in breast cancer cells has been poorly studied. We aimed to reveal the impact of B1 and B2 receptors on migration and invasion in breast cancer cells and demonstrate their capacity to modulate in vivo tumor growth. MDA-MB-231, MCF-7, and T47D cells treated with Lys-des[Arg

Indexed as

BradykininBreast NeoplasmsCell MovementFocal Adhesion Kinase 1Neoplasm InvasivenessReceptor, Bradykinin B1Receptor, Bradykinin B2src-Family KinasesAnimalsCell Line, TumorCell ProliferationFemaleFocal Adhesion Protein-Tyrosine KinasesHumansMCF-7 CellsMiceBradykininFocal Adhesion Kinase 1Focal Adhesion Protein-Tyrosine KinasesPTK2 protein, humanReceptor, Bradykinin B1Receptor, Bradykinin B2src-Family KinasesB1 receptorB2 receptorbreast cancerFAKinvasionkinin receptorsmigrationSrc

Identifiers

PMID39519260
PMCPMC11546324

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.